This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer phenomena. The book includes case studies, and a review of practical issues involved in bioreactor performance.
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Solid-State Fermentation Bioreactor Fundamentals: Introduction and Overview.- The Bioreactor Step of SSF: A Complex Interaction of Phenomena.- to Solid-State Fermentation Bioreactors.- Basics of Heat and Mass Transfer in Solid-State Fermentation Bioreactors.- The Scale-up Challenge for SSF Bioreactors.- Group I Bioreactors: Unaerated and Unmixed.- Group II Bioreactors: Forcefully-Aerated Bioreactors Without Mixing.- Group III: Rotating-Drum and Stirred-Drum Bioreactors.- Group IVa: Continuously-Mixed, Forcefully-Aerated Bioreactors.- Group IVb: Intermittently-Mixed Forcefully-Aerated Bioreactors.- Continuous Solid-State Fermentation Bioreactors.- Approaches to Modeling SSF Bioreactors.- Appropriate Levels of Complexity for Modeling SSF Bioreactors.- The Kinetic Sub-model of SSF Bioreactor Models: General Considerations.- Growth Kinetics in SSF Systems: Experimental Approaches.- Basic Features of the Kinetic Sub-model.- Modeling of the Effects of Growth on the Local Environment.- Modeling of Heat and Mass Transfer in SSF Bioreactors.- Substrate, Air, and Thermodynamic Parameters for SSF Bioreactor Models.- Estimation of Transfer Coefficients for SSF Bioreactors.- Bioreactor Modeling Case Studies: Overview.- A Model of a Well-mixed SSF Bioreactor.- A Model of a Rotating-Drum Bioreactor.- Models of Packed-Bed Bioreactors.- A Model of an Intermittently-Mixed Forcefully-Aerated Bioreactor.- Instrumentation for Monitoring SSF Bioreactors.- Fundamentals of Process Control.- Application of Automatic Control Strategies to SSF Bioreactors.- Design of the Air Preparation System for SSF Bioreactors.- Future Prospects for SSF Bioreactors.
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