Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research: v. 13 - Rilegato

Rilegato

ISBN 10: 3540583432 ISBN 13: 9783540583431

Casa editrice: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1994

Riassunto

A study of recent advances in metabolic research, focusing specifically on the mono-oxygenase cytochrome P450.

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Contenuti

1 Xenobiotic Metabolism: From Intact Biosystem to Single Enzymes.- 2 Regulation of Xenobiotic-Metabolizing Cytochromes P450.- 3 Cytochrome P450 in Human Drug Metabolism: How Much Is Predictable?.- 4 Metabolic Activation of Anticancer Oxazaphosphorines by Cytochrome P450s: Development of a Model for Cancer Gene Therapy.- 5 The Use of Bacteria for Cytochrome P450 Expression.- 6 Expression of Cytochromes P450 in Yeast: Practical Aspects.- 7 Human Cells as an Expression System for Cytochromes P450.- 8 Metabolic Reactions and Recombinant Isoenzymes of Cytochrome P450: Information Generated and Value for Pharmaceutical Development.- 9 The Importance of Cytochrome P450 3A Enzymes in Drug Metabolism.- 10 Strategies for Verifying the Involvement of Specific Cytochrome P450 Enzymes in Xenobiotic Metabolism.- 11 Regulation of Cytochromes P450 by Substrate Interactions.- 12 Strategies for the Use of Single Cytochrome P450 Enzymes in Drug Research and Future Prospects.

Product Description

European Book

Dettagli dell'edizione

• Editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Data di pubblicazione: 1994
• Lingua: Inglese
• ISBN 10: 3540583432
• ISBN 13: 9783540583431
• Rilegatura: Copertina rigida
• Numero di pagine: 239
• Redattore: Waterman Michael R., Hildebrand Milton
• Contatto del produttore: non disponibile
• Persona responsabile: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Germania