Normal and Abnormal Development of the Cortex - Rilegato

Libro 6 di 14: Research and Perspectives in Neurosciences
 
9783540632085: Normal and Abnormal Development of the Cortex

Sinossi

In keeping with IPSEN's growing interest in the neurosciences, the Fondation organized a meeting dealing with the topic of normal and abnormal cortical development, which took place in Paris, on October 14, 1996. This was the 7th of a series of colloquia devoted to the neurosciences. The topics covered included pre-migratory events controlling cell proliferation, neuronal migration, early cortical plasticity including cell death and development of axonal connections, and genetic and epigenetic effects on cortical teratogenesis. It is clear that the ultimate structure and functional capacity of the cerebral cortex are determined, at least in part, by developmental events taking place very early, even before neuronal migration. Caviness and colleagues suggest that the regulation of the G, portion of the cell cycle may be an important mechanism for determining neuronal class and pre-migratory positional encoding in the pseu­ dostratified periventricular germinal zones. Similarly, Kennedy and Dehay emphasize the role of pre-migratory cell cycle kinetics in the cytoarchitectonic differentiation of the cortex, but also consider some post-migratory events important to cortical differentiation. Among the post-migratory events control­ ling cortical differentiation are these thalamo-cortical connections, lind some of the rules governing this thalamo-cortical interaction was reviewed by Dennis O'Leary at the meeting. ' Three papers deal with the topic of neuronal migration. The paper by Hat­ ten and collaborators reviews the role of astrotactin and its cellular and molecu­ lar properties.

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Dalla quarta di copertina

This book, the seventh in the series "Research and Perspectives in Neuroscience", contains the procedings of a meeting that was held in Paris on October14, 1996. The conference consisted of invited papers and poster presentations. The invited papers, included in this volume, were on cell proliferation prior to neuronal migration, on cellular and molecular factors characteristic of neuronal migration, and on postmigrational neuronal and axonal plasticity. There was a section devoted to disorders of neuronal migration and plasticity and the genetics of some developmental disorders. Great strides have been made in this relatively young branch of modern neuroscience.

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9783642645907: Normal and Abnormal Development of the Cortex

Edizione in evidenza

ISBN 10:  3642645909 ISBN 13:  9783642645907
Casa editrice: Springer, 2011
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