Specificity, Function, and Development of Nk Cells: Nk Cells : The Effector Arm of Innate Immunity: Vol 230 - Rilegato

 
9783540639411: Specificity, Function, and Development of Nk Cells: Nk Cells : The Effector Arm of Innate Immunity: Vol 230
Rilegato
ISBN 10: 3540639411 ISBN 13: 9783540639411
Casa editrice: Springer Verlag, 1998

Sinossi

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Contenuti

A. NK Receptors and Coreceptors.- Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptors.- Stimulatory Receptors in NK and T Cells.- Killer Cell Inhibitory Receptor Expression by T Cells.- The CD94/NKG2 C-Type Lectin Receptor Complex.- Triggering of Natural Killer Cell Mediated Cytotoxicity by Costimulatory Molecules.- Fc Receptors on Natural Killer Cells.- Adhesion in NK Cell Function.- B. Activation of NK Cells and Effector Functions.- Signal Transduction During NK Cell Activation: Balancing Opposing Forces.- Effector Pathways of Natural Killer Cells.- C. Development of NK Cells.- Toward a Quantitative Analysis of the Repertoire of Class I MHC-Specific Inhibitory Receptors on Natural Killer Cells.- Ontogeny and Differentiation of Murine Natural Killer Cells and Their Receptors.- D. Role of NK Cells in Infections and Tumors.- Control of Infections by NK Cells.- Natural Killer Cells and Tumor Therapy.

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Springer Verlag
Data di pubblicazione
1998
Lingua
Inglese
ISBN 10 
3540639411
ISBN 13 
9783540639411
Rilegatura
Copertina rigida
Numero edizione
1
Numero di pagine
248
Redattore
Karre K., Colonna M.
Contatto del produttore
non disponibile
Persona responsabile
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Germania

Altre edizioni note dello stesso titolo

9783642468612: Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity: 230

Edizione in evidenza

ISBN 10:  3642468616 ISBN 13:  9783642468612
Casa editrice: Springer, 2012
Brossura