Articoli correlati a Intrabodies: Basic Research and Clinical Gene Therapy...

Intrabodies: Basic Research and Clinical Gene Therapy Applications - Rilegato

 
9783540641513: Intrabodies: Basic Research and Clinical Gene Therapy Applications
Rilegato
ISBN 10: 3540641513 ISBN 13: 9783540641513
Casa editrice: Springer Verlag, 1998

Sinossi

Antibodies have long been used in the biomedical sciences as in vitro tools for the identification, purification and functional manipulation of target antigens. They are also being exploited in vivo for diagnostic and therapeutic applications and play an important role in cancer and AIDS research. This book summarizes preclinical studies from laboratories worldwide that have used intrabodies - intracellular antibodies - for gene therapy and research applications.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Contenuti

1. Designing Intrabodies: Structural Features and the Use of Intracellular Trafficking Signals.- 2. Phage Libraries for Generation of Single Chain Fv Antibodies for Intracellular Immunization.- 3. Phenotypic Knockout of the Human Interleukin-2 Receptor ? Chain On Primary and HTLV-I Transformed T Cells.- 4. Intracellular Antibodies as Tools to Study ErbB Receptor Tyrosine Kinases.- 5. Neuroantibodies: The Use of Recombinant Antibody Expression in the Central Nervous System.- 6. Intracellular Antibody-Mediated Knockout of the ErbB-2 Oncoprotein as a Cancer Gene Therapy Approach.- 7. Intracellular Targeting of Oncogenes: A Novel Approach for Cancer Therapy.- 8. Intrabodies Against the HIV-1 Regulatory Proteins: Tat and Rev as Targets for Gene Therapy.- 9. Gene Therapy for HIV-1 Using Intracellular Antibodies Against HIV-1 Gag Proteins.- 10. Single Chain Variable Fragment-Based Strategies for Anti-HIV-1 Gene Therapy: Targeting the Viral Preintegration Complex and Combination Molecular Approaches.

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Springer Verlag
Data di pubblicazione
1998
Lingua
Inglese
ISBN 10 
3540641513
ISBN 13 
9783540641513
Rilegatura
Copertina rigida
Numero edizione
1
Numero di pagine
210
Redattore
Marasco Wayne A.
Contatto del produttore
non disponibile
Persona responsabile
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Germania