Redirection of Th1 and Th2 Responses: Vol 238 - Rilegato

Libro 167 di 253: Current Topics in Microbiology and Immunology
 
9783540650485: Redirection of Th1 and Th2 Responses: Vol 238

Sinossi

The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.

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Contenuti

List of Contents.- The Stability and Reversibility of Th1 and Th2 Populations.- T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases.- Redirecting Th2 Responses in Allergy.- Interleukin-12: Basic Principles and Clinical Applications.- Redirecting Th1 and Th2 Responses in Autoimmune Disease.- Manipulation of Th Responses by Oral Tolerance.

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Altre edizioni note dello stesso titolo

9783662097113: Redirection of Th1 and Th2 Responses: 238

Edizione in evidenza

ISBN 10:  3662097117 ISBN 13:  9783662097113
Casa editrice: Springer, 2013
Brossura