Glycoscience: Synthesis of Substrate Analogs and Mimetics (Springer Desktop Editions in Chemistry) - Brossura

Driguez, Hugues

Brossura

ISBN 10: 3540655468 ISBN 13: 9783540655466

Casa editrice: Springer, 1999

Riassunto

The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.

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Contenuti

Nucleophilic C-glycosyl donors for C-glycoside synthesis.- Synthesis of C-glycosides of biological interest.- Thiooligosaccharides in glycobiology.- Aldonolactones as chiral synthons.- Chemical and chemo-enzymatic approaches to glycosidase inhibitors with basic nitrogen in the sugar ring.- The synthesis of novel enzyme inhibitors and their use in defining the active sites of glycan hydrolases.- Heparinoid mimetics.- Recent developments in the rational design of multivalent glycoconjugates.- Amphiphilk carbohydrates as a tool for molecular recognition in organized systems.

Product Description

European Book

Dettagli dell'edizione

• Editore: Springer
• Data di pubblicazione: 1999
• Lingua: Inglese
• ISBN 10: 3540655468
• ISBN 13: 9783540655466
• Rilegatura: Copertina flessibile
• Numero di pagine: 336
• Contatto del produttore: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Germania