Sparking Signals: Kinases As Molecular Signaltransducers and Pharmacologial Drug Targets in Inflammation: Kinases as Molecular Signaltransducers and ... Drug Targets in Inflammation: 2007/3 - Rilegato

Rilegato

ISBN 10: 3540735003 ISBN 13: 9783540735007

Casa editrice: Springer Verlag, 2008

Riassunto

The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. In this book, well known experts present their most recent findings on the fast developing kinase field. It will be of interest to basic researchers and the pharmaceutical industry.

Su questo libro

Contenuti

Proteomics-Based Strategies in Kinase Drug Discovery.- PKC Isotype Functions in T Lymphocytes.- Migration, Cell–Cell Interaction and Adhesion in the Immune System.- Molecular Mechanisms that Control Leukocyte Extravasation Through Endothelial Cell Contacts.- Fragment-Based Drug Discovery Using Rational Design.- Systems Biology of T Cell Activation.- Solving the IRAK-4 Enigma: Application of Kinase-Dead Knock-In Mice.- Sensing, Presenting, and Regulating PAMPS.- The Role of Diacylglycerol Kinases in T Cell Anergy.

Product Description

Sparking Signals: Kinases As Molecular Signaltransducers And Pharmacologial Drug Targets In Inflammation BY Baier, G., Schraven, B., Zügel, U., Springer, Hardcover, 2008

Dettagli dell?edizione

• Editore: Springer Verlag
• Data di pubblicazione: 2008
• ISBN 10: 3540735003
• ISBN 13: 9783540735007
• Rilegatura: Copertina rigida
• Lingua: Inglese
• Numero edizione: 1
• Numero di pagine: 185
• Redattore: Baier G., Schraven B., Bonin A. V., Zugel U.
• Contatto del produttore: non disponibile