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Evolution of multiple alignments: Towards efficient data exploitation and knowledge extraction in the genomic era - Brossura
Genomics and proteomics technologies have led to a paradigm shift in bioinformatics, where the traditional reductionist approach is replaced by a more global, integrated view. In this context, multiple sequence alignments provide an ideal environment for the reliable integration of information from a complete genome to a gene and its related products. In this work, the sequence analysis field is reviewed and three example developments are described: (i) a benchmark for the objective evaluation of multiple alignment algorithms, (ii) a multiple alignment ontology (MAO) for nucleic acid or protein sequences and structures, (iii) an information management system (MACSIMS) that exploits the multiple alignment and the organisation provided by the ontology. The work is central to bioinformatics today and should be particularly useful to researchers working in various fields, such as genome analysis, target characterisation for structural proteomics, the study of human genetic pathologies, or the development of new drug discovery strategies.
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Dr. Thompson is a bioinformatics researcher at the National Centre for Scientific Research (CNRS) in France. She received her BSc degree in Mathematics at Sheffield University, UK and her PhD at the Louis Pasteur University, Strasbourg, France.
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- EditoreVDM Verlag
- Data di pubblicazione2009
- ISBN 10 3639169328
- ISBN 13 9783639169324
- RilegaturaCopertina flessibile
- Numero di pagine168
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Evolution of multiple alignments
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VDM Verlag Dr. Müller
(2009)
ISBN 10: 3639169328
ISBN 13: 9783639169324
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Descrizione libro Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Genomics and proteomics technologies have led to aparadigm shift in bioinformatics, where thetraditional reductionist approach is replaced by amore global, integrated view. In this context,multiple sequence alignments provide an idealenvironment for the reliable integration ofinformation from a complete genome to a gene and itsrelated products. In this work, the sequence analysisfield is reviewed and three example developments aredescribed: (i) a benchmark for the objectiveevaluation of multiple alignment algorithms, (ii) amultiple alignment ontology (MAO) for nucleic acid orprotein sequences and structures, (iii) aninformation management system (MACSIMS) that exploitsthe multiple alignment and the organisation providedby the ontology. The work is central tobioinformatics today and should be particularlyuseful to researchers working in various fields, suchas genome analysis, target characterisation forstructural proteomics, the study of human geneticpathologies, or the development of new drug discoverystrategies. 168 pp. Englisch. Codice articolo 9783639169324
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Evolution of multiple alignments
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VDM Verlag Dr. Müller
(2009)
ISBN 10: 3639169328
ISBN 13: 9783639169324
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Descrizione libro Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Thompson Julie DawnDr. Thompson is a bioinformatics researcher at the NationalnCentre for Scientific Research (CNRS) in France. She received hernBSc degree in Mathematics at Sheffield University, UK and her PhDnat the Louis Pasteur U. Codice articolo 4963689
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Evolution of multiple alignments : Towards efficient data exploitation and knowledge extraction in the genomic era
Editore:
VDM Verlag Dr. Müller
(2009)
ISBN 10: 3639169328
ISBN 13: 9783639169324
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Taschenbuch
Quantità: 2
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Descrizione libro Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Genomics and proteomics technologies have led to aparadigm shift in bioinformatics, where thetraditional reductionist approach is replaced by amore global, integrated view. In this context,multiple sequence alignments provide an idealenvironment for the reliable integration ofinformation from a complete genome to a gene and itsrelated products. In this work, the sequence analysisfield is reviewed and three example developments aredescribed: (i) a benchmark for the objectiveevaluation of multiple alignment algorithms, (ii) amultiple alignment ontology (MAO) for nucleic acid orprotein sequences and structures, (iii) aninformation management system (MACSIMS) that exploitsthe multiple alignment and the organisation providedby the ontology. The work is central tobioinformatics today and should be particularlyuseful to researchers working in various fields, suchas genome analysis, target characterisation forstructural proteomics, the study of human geneticpathologies, or the development of new drug discoverystrategies. Codice articolo 9783639169324
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Evolution Of Multiple Alignments: Towards Efficient Data Exploitation And Knowledge Extraction In The Genomic Era
Editore:
Vdm Verlag Dr. Müller
(2009)
ISBN 10: 3639169328
ISBN 13: 9783639169324
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Descrizione libro Paperback. Condizione: Brand New. 168 pages. 8.66x5.91x0.38 inches. In Stock. Codice articolo zk3639169328
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