Lipopolysaccharide Effect on RBC Volume in an In-Vitro Model: Mean Corpuscular Volume Analysis by Micropipette Aspiration Technique before and after Activated Protein C Application - Brossura

El Hage, Rabih

Brossura

ISBN 10: 3639279255 ISBN 13: 9783639279252

Casa editrice: VDM Verlag Dr. Müller, 2010

Riassunto

Recent studies about lipopolysaccharide (LPS) effects were done on red blood cells in in-vivo and in in-vitro models showed that sepsis (or gram negative bacterial sepsis like LPS infection) had effect on red blood cells. Previous studies showed already the immediate anti- aggregant effect of lipopolysaccharide on red blood cells. Remarkably through those experiments, the red blood cells diameter looked as if it increased, judging only by naked eye from saved videos and microscopic images. But there was no specific confirmation that the red blood cells volume did also increase. There comes the need of micropipette aspiration technique, which is itself an accurate single cell technique that carries some very precise tasks, including the determination of red blood cells volume, in our case, the volume change of red blood cells exposed to many chemicals and proteins including lipopolysaccharide and activated protein C (APC).

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Informazioni sull?autore

Rabih El Hage, Dipl.-Ing. (FH) Studium der Medizintechnik an der FH Aachen. Verkaufsspezialist bei der Mediline s.a.r.l. - Libanon

Dettagli dell'edizione

• Editore: VDM Verlag Dr. Müller
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 3639279255
• ISBN 13: 9783639279252
• Rilegatura: Copertina flessibile
• Numero di pagine: 88
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile