Synthesis of Highly Functionalized Pyrazoles Using Ketene Dithioacetal - Brossura

Savant, Mahesh; Audichya, Vipul

Brossura

ISBN 10: 3639715292 ISBN 13: 9783639715293

Casa editrice: Scholars' Press, 2014

Riassunto

In recent decades, the tremendous biological potential of the highly substituted pyrazole scaffolds have attracted many chemists to synthesize this class of molecules. The classical methods to synthesized pyrazoles and involves the condensation of diketone compound or its synthetic equivalent with hydrazine in appropriate organic solvent. On the other hand, functionalized ketene dithioacetals are versatile intermediates in organic synthesis for the construction of substituted heterocycles such as pyrazoles. Thus, the practical synthesis of poly substituted pyrazole based small molecules is of great importance. The present research has demonstrated the synthesis of highly functionalized Pyrazoles using ketene dithioacetal and followed by N-alkylation using TBAB and water as solvent in excellent yield and its biological study.

Dettagli dell'edizione

• Editore: Scholars' Press
• Data di pubblicazione: 2014
• Lingua: Inglese
• ISBN 10: 3639715292
• ISBN 13: 9783639715293
• Rilegatura: Copertina flessibile
• Numero di pagine: 68
• Redattore: Naliapara Yogesh
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile