Sinossi
This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally comprehensive treatment of the subject, summarizing all existing views on the topic and at the same time putting them into context. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field.
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Dalla quarta di copertina
Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage, which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. Until recently, much of our knowledge on the mechanisms of genetic recombination has come from studies of prokaryotic and simple eukaryotic fungal systems. However, these studies have now been significantly extended to mammals, such that a comparative picture of the general factors and mechanisms of genetic recombination is beginning to emerge. Detailed genetic and biochemical studies have led to the isolation and characterization of many of the recombination-repair proteins in E. coli and S. cerevisiae, which in turn has led to the identification of homologues in human cells. The link between recombination defects and recombination proteins in a number of tumors as well as in human hereditary syndromes makes genetic recombination a cellular process of key importance not only in basic biology but also in biomedical studies.
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Molecular Genetics of Recombination (eng)
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Covers one of the most important topics in modern biology: recombinationSummarize all existing views on the topic and to put them into contextIn-depth and up-to-date analysis of the chapter topics, written by international experts. Codice articolo 5048030
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Molecular Genetics of Recombination
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Springer Berlin Heidelberg Nov 2010, 2010
ISBN 10: 3642090052
ISBN 13: 9783642090059
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally comprehensive treatment of the subject, summarizing all existing views on the topic and at the same time putting them into context. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field. 548 pp. Englisch. Codice articolo 9783642090059
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Molecular Genetics of Recombination
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Taschenbuch. Condizione: Neu. Molecular Genetics of Recombination | Andrés Aguilera (u. a.) | Taschenbuch | Topics in Current Genetics | xxiv | Englisch | 2010 | Springer | EAN 9783642090059 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Codice articolo 107212012
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Molecular Genetics of Recombination
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Springer, Springer Spektrum Nov 2010, 2010
ISBN 10: 3642090052
ISBN 13: 9783642090059
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book covers one of the most important topics in modern biology: recombination. Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. The book summarizes all existing views on the topic and puts them into context. It contains in-depth and up-to-date analysis of the chapter topics, written by international experts.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 548 pp. Englisch. Codice articolo 9783642090059
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Molecular Genetics of Recombination
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Springer Berlin Heidelberg, 2010
ISBN 10: 3642090052
ISBN 13: 9783642090059
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage, which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. Until recently, much of our knowledge on the mechanisms of genetic recombination has come from studies of prokaryotic and simple eukaryotic fungal systems. However, these studies have now been significantly extended to mammals, such that a comparative picture of the general factors and mechanisms of genetic recombination is beginning to emerge. Detailed genetic and biochemical studies have led to the isolation and characterization of many of the recombination-repair proteins in E. coli and S. cerevisiae, which in turn has led to the identification of homologues in human cells. The link between recombination defects and recombination proteins in a number of tumors as well as in human hereditary syndromes makes genetic recombination a cellular process of key importance not only in basic biology but also in biomedical studies. Codice articolo 9783642090059
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Molecular Genetics of Recombination (Topics in Current Genetics, 17)
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Molecular Genetics of Recombination (Topics in Current Genetics)
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Paperback. Condizione: Brand New. reprint edition. 548 pages. 9.29x5.98x1.18 inches. In Stock. Codice articolo x-3642090052
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