Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation: 2007/3 - Brossura
Sinossi
Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
Proteomics-Based Strategies in Kinase Drug Discovery.- PKC Isotype Functions in T Lymphocytes.- Migration, Cell–Cell Interaction and Adhesion in the Immune System.- Molecular Mechanisms that Control Leukocyte Extravasation Through Endothelial Cell Contacts.- Fragment-Based Drug Discovery Using Rational Design.- Systems Biology of T Cell Activation.- Solving the IRAK-4 Enigma: Application of Kinase-Dead Knock-In Mice.- Sensing, Presenting, and Regulating PAMPS.- The Role of Diacylglycerol Kinases in T Cell Anergy.
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Sparking Signals
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Springer, Springer Nov 2010, 2010
ISBN 10: 3642092624
ISBN 13: 9783642092626
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups. 204 pp. Englisch. Codice articolo 9783642092626
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Internationally well known experts presented their most recent findings on the fast developing kinase fieldOutstanding interest for basic researchers and pharmaceutical industryThe importance of the protein kinase family is underscored . Codice articolo 5048280
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Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation (Ernst Schering Foundation Symposium Proceedings)
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Sparking Signals | Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation
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Taschenbuch. Condizione: Neu. Sparking Signals | Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation | Gottfried Baier (u. a.) | Taschenbuch | xiv | Englisch | 2010 | Springer | EAN 9783642092626 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Codice articolo 107176053
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Sparking Signals
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Protein phosphorylation is an essential post-translational modification that modulates cell¿cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch. Codice articolo 9783642092626
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Sparking Signals : Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation
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Springer Berlin Heidelberg, 2010
ISBN 10: 3642092624
ISBN 13: 9783642092626
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups. Codice articolo 9783642092626
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Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation (Ernst Schering Foundation Symposium Proceedings)
Da: Revaluation Books, Exeter, Regno Unito
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Paperback. Condizione: Brand New. 201 pages. 8.00x5.00x0.48 inches. In Stock. Codice articolo 3642092624
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