Sinossi
Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
The APOBEC3 Family of Retroelement Restriction Factors
Eric W. Refsland and Reuben S. Harris
Inhibition of Retroviral Replication by Members of the TRIM Protein Family
Adam J Fletcher and Greg J Towers
The Antiviral Activities of Tetherin
Stuart J D Neil
Restriction of Retroviral Infection of Macrophages
Mark Sharkey
Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors
Welkin E. Johnson
RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants
Szittya György and József Burgyán
RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates
Arabinda Nayak, Michel Tassetto, Mark Kunitomi and Raul Andino
Roles of MicroRNAs in the Life Cycles of Mammalian Viruses
Eva Gottwein
Interplay Between DNA Tumor Viruses and the Host DNA Damage Response
Karyn McFadden and Micah Luftig
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Risultati della ricerca per Intrinsic Immunity: 371
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Intrinsic immunity.
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Heidelberg/New York, NY/Dordrecht/London/Berlin, Springer., 2013
ISBN 10: 3642377645
ISBN 13: 9783642377648
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VII, 262 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Stamped. Current topics in microbiology and immunology ; Vol. 371. Sprache: Englisch. Codice articolo 5656EB
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Intrinsic Immunity
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted. 272 pp. Englisch. Codice articolo 9783642377648
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch. Codice articolo 9783642377648
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Intrinsic Immunity
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ISBN 10: 3642377645
ISBN 13: 9783642377648
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted. Codice articolo 9783642377648
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