Microbial Ribonucleases: 6 - Brossura

Egami, Fujio; Nakamura, K.

Brossura

ISBN 10: 3642875009 ISBN 13: 9783642875007

Casa editrice: Springer, 2012

Riassunto

Studies on microbial RNases began in 1924 when NOGUCHI found nucleic acid degrading enzymes in Takadiastase, a commercially prepared digest from Aspergillus oryzae. In 1935 OrANI reported the presence of enzymes degrading yeast RNA in fungi (Aspergillus sp. etc.). In 1948, MCCARTY studied the nuclease activity in 36 strains of group A hemolytic Streptococci and indicated the release of both RNase and DNase from Streptococcal cells during growth in culture media. As is well known, these nucleases (TILLETT et al., 1948) are applied in the treatment of inflammatory exudates. In 1952, MUGGLETON and WEBB found RNase in the culture medium of Actinomy­ ces (strain A), and they suggested that the ability of the medium to render killed Gram-positive cells Gram-negative may be due to the RNase. In the same year PARDEE and his colleagues (1952 a, b) found RNase activity in E. coli (strain B) in­ fected by bacteriophage T r, T3 etc. 2 KUNINAKA (1954) found ribonuclease in culture @trates of Aspergillus oryzae.

Su questo libro

Contenuti

I. Introduction.- II. Classification of Enzymes Attacking RNA.- III. Distribution of RNases in Microorganisms.- Microorganisms of which RNA-Degrading Enzymes have been Investigated.- IV. Chemical Studies on Microbial RNases.- A. Introduction.- B. RNases of Aspergillus oryzae.- 1. RNase T1.- 2. RNase T2.- C. RNases of Streptomyces and Actinomyces.- 1. RNase of Streptomyces erythreus.- 2. RNase of Streptomyces albogriceolus.- 3. RNase of Actinomyces aureoverticillatus.- D. RNases of Ustilago.- 1. RNases of Ustilagosphaerogena and Ustilago zeae.- E. RNases of Neurospora crassa.- F. RNases of Azotobacter agilis (vinelandii).- G. RNase I of E. coli.- H. RNase of Aspergillus saitoi.- I. RNase of Bacillus subtilis.- 1. Extracellular RNases of Bacillus subtilis Strain H.- 2. Extracellular RNase of Bacillus subtilis Marburg Strain.- 3. Intracellular RNase of Bacillus subtilis.- J. Yeast RNase.- K. RNase II of E. coli.- L. RNase III of E. coli.- M. General Considerations.- 1. Ribonucleate Guaninenucleotido-2?-transferase (Cyclizing).- 2. Ribonucleate Purinenucleotido-2?-transferase (Cyclizing).- 3. Ribonucleate Ribonucleotido-2?-transferase (Cyclizing).- 4. Other RNases.- V. Physiological Role of RNA-Degrading Enzymes in Microorganisms.- A. Introduction.- B. Role of Intracellular Enzymes with Special Reference to E. coli.- 1. Mode of Existence.- a) Ribonuclease I (Ribosomal “Latent” Ribonuclease).- b) Ribonuclease II (Potassium Activated Ribonuclease).- c) Polynucleotide Phosphorylase.- 2. Physiological Role.- a) Roles in Metabolism of RNA.- b) Other Probable Roles.- 3. Control Mechanism of RNase Activity.- C. Role of Extracellular Enzymes.- VI. Concluding Remarks.- References.

Dettagli dell'edizione

• Editore: Springer
• Data di pubblicazione: 2012
• Lingua: Inglese
• ISBN 10: 3642875009
• ISBN 13: 9783642875007
• Rilegatura: Copertina flessibile
• Numero di pagine: 104
• Contatto del produttore: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Germania