Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation - Brossura

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Loos, Carolin

 
9783658132330: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation
Brossura
ISBN 10: 3658132337 ISBN 13: 9783658132330
Casa editrice: Springer Spektrum, 2016

Sinossi

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information. 

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Informazioni sull?autore

Carolin Loos is currently doing her PhD at the Institute ofComputational Biology at the Helmholtz Zentrum München. She is member of thejunior research group „Data-driven Computational Modeling“. 

Dalla quarta di copertina

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.

Contents

  • Modeling and Parameter Estimation for Single-Cell Data
  • ODE Constrained Mixture Modeling for Multivariate Data
  • Approximate Bayesian Computation Using Multivariate Statistics

Target Groups

    Researchers and students in the fields of (bio-)mathematics, statistics, bioinformatics
  • System biologists, biostatisticians, bioinformaticians

The Author
Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group Data-driven Computational Modeling .


Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Springer Spektrum
Data di pubblicazione
2016
Lingua
Inglese
ISBN 10 
3658132337
ISBN 13 
9783658132330
Rilegatura
Copertina flessibile
Numero edizione
1
Numero di pagine
116
Contatto del produttore
non disponibile
Persona responsabile
non disponibile

Altre edizioni note dello stesso titolo

9783658132354: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation

Edizione in evidenza

ISBN 10:  3658132353 ISBN 13:  9783658132354
Casa editrice: Springer Spektrum, 2016
Brossura