Articoli correlati a Design and Development of Extended Release Tablet of...
Design and Development of Extended Release Tablet of Nicotinic acid: The formulation deduction of drug flushing - Brossura
Sinossi
Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in immediate release dosage form. The tablets were prepared by wet granulation method using HPMC K-15M, polymer as retardant and the prepared tablets of NA will remain intact up to 2 hrs in pH 1.2 due to Eudragit L 100-55 and its release is not only initiated but tact fully retarded up to 12 hrs and were found to be superior in physical properties,dissolution characteristics, and drug content uniformity. The drug release from the matrix tablet Fitted to the Higuchi model and Zero order release which indicates non-Fickian diffusion.N8 showed good similarity with theoretical profile of nicotinic acid. Excipients has significant effect on drug release,because DCP retarded the release due to hydrophobic nature, on the contrary MCC increased drug release for its swelling property and causing burst release, and lactose moderately affected drug release due to channeling action and hence causing drug release at desired rate and amount. The studies indicate that the formulation was effective in providing in vitro release for extended period.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Informazioni sull'autore
Mr. Brijeshkumar Chaudhari has obtained M. Pharm Degree in Pharmaceutics specialization in 2012. He is the author with several articles published in journals.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Risultati della ricerca per Design and Development of Extended Release Tablet of...
Immagini fornite dal venditore
Design and Development of Extended Release Tablet of Nicotinic acid
Editore:
LAP LAMBERT Academic Publishing Jun 2012, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Nuovo
Taschenbuch
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in immediate release dosage form. The tablets were prepared by wet granulation method using HPMC K-15M, polymer as retardant and the prepared tablets of NA will remain intact up to 2 hrs in pH 1.2 due to Eudragit L 100-55 and its release is not only initiated but tact fully retarded up to 12 hrs and were found to be superior in physical properties,dissolution characteristics, and drug content uniformity. The drug release from the matrix tablet Fitted to the Higuchi model and Zero order release which indicates non-Fickian diffusion.N8 showed good similarity with theoretical profile of nicotinic acid. Excipients has significant effect on drug release,because DCP retarded the release due to hydrophobic nature, on the contrary MCC increased drug release for its swelling property and causing burst release, and lactose moderately affected drug release due to channeling action and hence causing drug release at desired rate and amount. The studies indicate that the formulation was effective in providing in vitro release for extended period. 120 pp. Englisch. Codice articolo 9783659151880
Compra nuovo
EUR 59,00
Spedizione EUR 23,00
Spedito da Germania a U.S.A.
Spedito da Germania a U.S.A.
Quantità: 2 disponibili
Immagini fornite dal venditore
Design and Development of Extended Release Tablet of Nicotinic acid
Editore:
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Nuovo
Brossura
Da: moluna, Greven, Germania
Valutazione del venditore 5 su 5 stelle
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chaudhari BrijeshkumarMr. Brijeshkumar Chaudhari has obtained M. Pharm Degree in Pharmaceutics specialization in 2012. He is the author with several articles published in journals.Nicotinic acid (NA) as lipid lowering agent drug . Codice articolo 5135256
Compra nuovo
EUR 48,50
Spedizione EUR 48,99
Spedito da Germania a U.S.A.
Spedito da Germania a U.S.A.
Quantità: Più di 20 disponibili
Immagini fornite dal venditore
Design and Development of Extended Release Tablet of Nicotinic acid
Editore:
LAP LAMBERT Academic Publishing Jun 2012, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Nuovo
Taschenbuch
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in immediate release dosage form. The tablets were prepared by wet granulation method using HPMC K-15M, polymer as retardant and the prepared tablets of NA will remain intact up to 2 hrs in pH 1.2 due to Eudragit L 100-55 and its release is not only initiated but tact fully retarded up to 12 hrs and were found to be superior in physical properties,dissolution characteristics, and drug content uniformity. The drug release from the matrix tablet Fitted to the Higuchi model and Zero order release which indicates non-Fickian diffusion.N8 showed good similarity with theoretical profile of nicotinic acid. Excipients has significant effect on drug release,because DCP retarded the release due to hydrophobic nature, on the contrary MCC increased drug release for its swelling property and causing burst release, and lactose moderately affected drug release due to channeling action and hence causing drug release at desired rate and amount. The studies indicate that the formulation was effective in providing in vitro release for extended period.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 120 pp. Englisch. Codice articolo 9783659151880
Compra nuovo
EUR 59,00
Spedizione EUR 60,00
Spedito da Germania a U.S.A.
Spedito da Germania a U.S.A.
Quantità: 1 disponibili
Immagini fornite dal venditore
Design and Development of Extended Release Tablet of Nicotinic acid : The formulation deduction of drug flushing
Editore:
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Nuovo
Taschenbuch
Da: AHA-BUCH GmbH, Einbeck, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in immediate release dosage form. The tablets were prepared by wet granulation method using HPMC K-15M, polymer as retardant and the prepared tablets of NA will remain intact up to 2 hrs in pH 1.2 due to Eudragit L 100-55 and its release is not only initiated but tact fully retarded up to 12 hrs and were found to be superior in physical properties,dissolution characteristics, and drug content uniformity. The drug release from the matrix tablet Fitted to the Higuchi model and Zero order release which indicates non-Fickian diffusion.N8 showed good similarity with theoretical profile of nicotinic acid. Excipients has significant effect on drug release,because DCP retarded the release due to hydrophobic nature, on the contrary MCC increased drug release for its swelling property and causing burst release, and lactose moderately affected drug release due to channeling action and hence causing drug release at desired rate and amount. The studies indicate that the formulation was effective in providing in vitro release for extended period. Codice articolo 9783659151880
Compra nuovo
EUR 59,71
Spedizione EUR 60,99
Spedito da Germania a U.S.A.
Spedito da Germania a U.S.A.
Quantità: 1 disponibili
Immagini fornite dal venditore
Design and Development of Extended Release Tablet of Nicotinic acid | The formulation deduction of drug flushing
Editore:
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Nuovo
Taschenbuch
Da: preigu, Osnabrück, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. Design and Development of Extended Release Tablet of Nicotinic acid | The formulation deduction of drug flushing | Brijeshkumar Chaudhari (u. a.) | Taschenbuch | 120 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783659151880 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Codice articolo 106417966
Compra nuovo
EUR 51,10
Spedizione EUR 70,00
Spedito da Germania a U.S.A.
Spedito da Germania a U.S.A.
Quantità: 5 disponibili
Foto dell'editore
Design and Development of Extended Release Tablet of Nicotinic acid: The formulation deduction of drug flushing
Editore:
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659151882
ISBN 13: 9783659151880
Antico o usato
Paperback
Da: Mispah books, Redhill, SURRE, Regno Unito
Valutazione del venditore 4 su 5 stelle
Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book. Codice articolo ERICA79636591518826
Compra usato
EUR 139,42
Spedizione EUR 29,17
Spedito da Regno Unito a U.S.A.
Spedito da Regno Unito a U.S.A.
Quantità: 1 disponibili