Development And Validation Of Analytical Methods: Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form - Brossura
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Two UV-Spectrophotometric and RP-HPLC methods have been developed and validated for estimation of Amlodipine Besilate and Indapamide simultaneously.In absorbance correction method absorbance was measured at 360 nm for Amlodipine Besilate and at 242 nm for Indapamide. In First order Spectrophotometry method, the dA/dλ value in first order derivative spectra was measured at 242 nm for Amlodipine Besilate and 238 nm for Indapamide. The proposed methods were utilized for estimation of Amlodipine Besilate and Indapamide in tablet dosage form. RP-HPLC method showed adequate separation of Amlodipine Besilate and Indapamide. Amlodipine Besilate and Indapamide were estimated on C18 column using Acetonitrile: Water (contains 0.2% of Triethylamine and adjusting the pH to 4.0 with 10 % orthophosphoric acid) in a proportion of 70:30 v/v as mobile phase and detection was carried out at 238 nm. Results of Validation study and assay of all three methods were found to be satisfactory. The developed method were statistically compared using one way ANOVA which suggest that there is no significance difference among all three methods.
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L'autore
Mehul M. Patel (M.Pharm., Pharmaceutical Chemistry)Professional SummaryAssistant Professor with Five years of experience.Specialty areas include Medicinal Chemistry, Analytical technology and Pharmaceutical Chemistry.
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Development And Validation Of Analytical Methods
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LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659256099
ISBN 13: 9783659256097
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Patel MehulMehul M. Patel (M.Pharm., Pharmaceutical Chemistry)Professional SummaryAssistant Professor with Five years of experience.Specialty areas include Medicinal Chemistry, Analytical technology and Pharmaceutical Chemistry.T. Codice articolo 5143505
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Development And Validation Of Analytical Methods: Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form
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Lap Lambert Academic Publishing, 2012
ISBN 10: 3659256099
ISBN 13: 9783659256097
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Paperback. Condizione: Brand New. 100 pages. 8.66x5.91x0.23 inches. In Stock. Codice articolo 3659256099
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Development And Validation Of Analytical Methods : Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form
Editore:
LAP Lambert Academic Publishing, 2012
ISBN 10: 3659256099
ISBN 13: 9783659256097
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Two UV-Spectrophotometric and RP-HPLC methods have been developed and validated for estimation of Amlodipine Besilate and Indapamide simultaneously.In absorbance correction method absorbance was measured at 360 nm for Amlodipine Besilate and at 242 nm for Indapamide. In First order Spectrophotometry method, the dA/d value in first order derivative spectra was measured at 242 nm for Amlodipine Besilate and 238 nm for Indapamide. The proposed methods were utilized for estimation of Amlodipine Besilate and Indapamide in tablet dosage form. RP-HPLC method showed adequate separation of Amlodipine Besilate and Indapamide. Amlodipine Besilate and Indapamide were estimated on C18 column using Acetonitrile: Water (contains 0.2% of Triethylamine and adjusting the pH to 4.0 with 10 % orthophosphoric acid) in a proportion of 70:30 v/v as mobile phase and detection was carried out at 238 nm. Results of Validation study and assay of all three methods were found to be satisfactory. The developed method were statistically compared using one way ANOVA which suggest that there is no significance difference among all three methods. Codice articolo 9783659256097
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Development And Validation Of Analytical Methods | Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form
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LAP Lambert Academic Publishing, 2012
ISBN 10: 3659256099
ISBN 13: 9783659256097
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Taschenbuch. Condizione: Neu. Development And Validation Of Analytical Methods | Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form | Mehul Patel (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783659256097 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Codice articolo 106219747
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