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The aim of present study was to formulate and evaluate the mouth dissolving tablets of flurbiprofen using various superdisintegrants for rapid disintegration, to improve patient compliance and to obtain disintegration time <30 sec. Effect of varying concentration of various superdisintegrants such as crosspovidone, croscarmellose sodium, sodium starch glycolate (SSG) on disintegration time and wetting time was studied. DSC study showed that, there is no drug excipients interaction. Tablets were prepared using direct compression method and were evaluated for hardness, friability, drug content, In vitro disintegration time, wetting time, and In vitro drug release. The results of disintegrating time and wetting time of tablets prepared using croscarmellose sodium and SSG were significantly superior compared to superdisintegrants. The optimization of formulation was done by using 32 full factorial designs. A 32 full factorial design was applied to systematically optimize the drug disintegration time, wetting time and drug release. The concentration of SSG(X1) and concentration of Croscarmellose(X2) were selected as independent variables.
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Informazioni sull'autore
Ms.Amita Yadav resident of Gandhinagar and did her M.Pharm. in Industrial Pharmacy in 2013 from S.K.P.C.P.E.R., Ganpat University, Kherva (Mehsana)-Guj.She did B.Pharm. from BN Girls' College of Pharmacy, Udaipur. She has many review and research scientific publications and presentations to her credit, Research is her core area of interest.
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Formulation, Evaluation and Optimization of Mouth Dissolving Tablets
Editore:
LAP LAMBERT Academic Publishing Jul 2014, 2014
ISBN 10: 3659575836
ISBN 13: 9783659575839
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of present study was to formulate and evaluate the mouth dissolving tablets of flurbiprofen using various superdisintegrants for rapid disintegration, to improve patient compliance and to obtain disintegration time 30 sec. Effect of varying concentration of various superdisintegrants such as crosspovidone, croscarmellose sodium, sodium starch glycolate (SSG) on disintegration time and wetting time was studied. DSC study showed that, there is no drug excipients interaction. Tablets were prepared using direct compression method and were evaluated for hardness, friability, drug content, In vitro disintegration time, wetting time, and In vitro drug release. The results of disintegrating time and wetting time of tablets prepared using croscarmellose sodium and SSG were significantly superior compared to superdisintegrants. The optimization of formulation was done by using 32 full factorial designs. A 32 full factorial design was applied to systematically optimize the drug disintegration time, wetting time and drug release. The concentration of SSG(X1) and concentration of Croscarmellose(X2) were selected as independent variables. 128 pp. Englisch. Codice articolo 9783659575839
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Formulation, Evaluation and Optimization of Mouth Dissolving Tablets
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LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659575836
ISBN 13: 9783659575839
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Da: AHA-BUCH GmbH, Einbeck, Germania
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of present study was to formulate and evaluate the mouth dissolving tablets of flurbiprofen using various superdisintegrants for rapid disintegration, to improve patient compliance and to obtain disintegration time 30 sec. Effect of varying concentration of various superdisintegrants such as crosspovidone, croscarmellose sodium, sodium starch glycolate (SSG) on disintegration time and wetting time was studied. DSC study showed that, there is no drug excipients interaction. Tablets were prepared using direct compression method and were evaluated for hardness, friability, drug content, In vitro disintegration time, wetting time, and In vitro drug release. The results of disintegrating time and wetting time of tablets prepared using croscarmellose sodium and SSG were significantly superior compared to superdisintegrants. The optimization of formulation was done by using 32 full factorial designs. A 32 full factorial design was applied to systematically optimize the drug disintegration time, wetting time and drug release. The concentration of SSG(X1) and concentration of Croscarmellose(X2) were selected as independent variables. Codice articolo 9783659575839
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Formulation, Evaluation and Optimization of Mouth Dissolving Tablets
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ISBN 10: 3659575836
ISBN 13: 9783659575839
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Da: moluna, Greven, Germania
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Yadav AmitaMs.Amita Yadav resident of Gandhinagar and did her M.Pharm. in Industrial Pharmacy in 2013 from S.K.P.C.P.E.R., Ganpat University, Kherva (Mehsana)-Guj.She did B.Pharm. from BN Girls College of Pharmacy, Udaipur. She has . Codice articolo 5165930
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Formulation, Evaluation and Optimization of Mouth Dissolving Tablets
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LAP LAMBERT Academic Publishing Jul 2014, 2014
ISBN 10: 3659575836
ISBN 13: 9783659575839
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The aim of present study was to formulate and evaluate the mouth dissolving tablets of flurbiprofen using various superdisintegrants for rapid disintegration, to improve patient compliance and to obtain disintegration timeVDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 128 pp. Englisch. Codice articolo 9783659575839
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Formulation, Evaluation and Optimization of Mouth Dissolving Tablets
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LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659575836
ISBN 13: 9783659575839
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Taschenbuch. Condizione: Neu. Formulation, Evaluation and Optimization of Mouth Dissolving Tablets | Amita Yadav (u. a.) | Taschenbuch | 128 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659575839 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Codice articolo 105176008
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