Articoli correlati a Complement And Kidney Disease
Sinossi
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
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Contenuti
The complement system in renal diseases.- Complement in renal transplantation.- C1q and the glomerulonephritides: therapeutic approaches for the treatment of complement-mediated kidney diseases.- Complement deficient mice as model systems for kidney diseases.- Non-Shiga toxin-associated hemolytic uremic syndrome.- Role of complement and Factor H in hemolytic uremic syndrome.- Genetic testing in atypical HUS and the role of membrane cofactor protein (MCP; CD46) and Factor I.- Towards a new classification of hemolytic uremic syndrome.- Therapeutic strategies for atypical and recurrent hemolytic uremic syndromes (HUS).- Complement defects in children which result in kidney diseases: diagnosis and therapy.- The role of complement in membranoproliferative glomerulonephritis.- The experience of a patient advocacy group.
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Book by Zipfel Peter F
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Complement and Kidney Disease (Progress in Inflammation Research)
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Complement And Kidney Disease (progress In Inflammation Research)
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Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service. Codice articolo ABEOCT25-247075
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Complement and Kidney Disease (Progress in Inflammation Research)
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Complement and Kidney Disease (Progress in Inflammation Research)
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Complement and Kidney Disease
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Springer, Basel, Birkhäuser Basel, Birkhäuser Dez 2005, 2005
ISBN 10: 3764371668
ISBN 13: 9783764371661
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume. 236 pp. Englisch. Codice articolo 9783764371661
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Complement and Kidney Disease
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Role of genetic mutations in regulator proteinsNew therapies in human kidney diseasesProf. Zipfel is a well renowned scientist in this area of researchThe understanding how complement relates to glomerular diseaseshas evolved con. Codice articolo 5279624
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Complement and Kidney Disease
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Condizione: New. It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. This book discusses Molecular biology, clinics and therapy. Editor(s): Zipfel, Peter F. Series: Progress in Inflammation Research. Num Pages: 252 pages, biography. BIC Classification: MFG; MJCM; MJR; MMFM; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 16. Weight in Grams: 603. . 2005. 2006th Edition. hardcover. . . . . Codice articolo V9783764371661
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