Articoli correlati a Sinus node inhibitors: A new concept in angina pectoris
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Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment.
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Contenuti
Reduction of heart rate ― Really a new concept in treating angina pectoris?.- ULFS 49 CL, a prototype of a novel pharmacological concept.- Sinus node inhibitors for reducing exercise-induced myocardial ischemia: Evidence from experimental animal studies.- Electrophysiological effects of ULFS 49 CL.- Antiischemic, antianginal, and hemodynamic effects of ULFS 49 CL (a new heart-rate-reducing agent) in patients with angiographically proven CAD.- Efficacy and duration of action of three doses of Zatebradine (ULFS 49 CL) in patients with chronic angina pectoris compared to placebo.
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Sinus node inhibitors
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress, thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment. 76 pp. Englisch. Codice articolo 9783798508613
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Sinus Node Inhibitors : A New Concept in Angina Pectoris
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Sinus Node Inhibitors
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Condizione: New. This volume addresses a novel concept in antiischemic therapy, sinus node inhibition. The sinus node inhibitors which have thus far been developed, including the clonidine-derivative alinidine, falipamil and the benzazepinone derivative UL FS 49, are discussed in detail. Editor(s): Hjalmarson, A.; Remme, W. J. Num Pages: 64 pages, 3 black & white illustrations, biography. BIC Classification: MJD; MMG. Category: (P) Professional & Scholarly; (UP) Postgraduate. Dimension: 244 x 170 x 4. Weight in Grams: 137. . 1991. Paperback. . . . . Codice articolo V9783798508613
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Sinus node inhibitors: A new concept in angina pectoris
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Sinus node inhibitors : A new concept in angina pectoris
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress, thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment. Codice articolo 9783798508613
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Sinus node inhibitors | A new concept in angina pectoris
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Taschenbuch. Condizione: Neu. Sinus node inhibitors | A new concept in angina pectoris | W. J. Remme (u. a.) | Taschenbuch | viii | Englisch | 1991 | Steinkopff | EAN 9783798508613 | Verantwortliche Person für die EU: Steinkopff, Dietrich Verlag in Springer Science + Business M, Tiergartenstr. 15-17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 102112532
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Sinus node inhibitors
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Sinus Node Inhibitors: A New Concept in Angina Pectoris
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Paperback. Condizione: Brand New. 1st edition. 76 pages. Delaware language. 9.61x6.69x0.18 inches. In Stock. Codice articolo x-3798508615
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Sinus node inhibitors
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress, thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment.Steinkopff Dr. Dietrich V, Poststr. 9, 64293 Darmstadt 76 pp. Englisch. Codice articolo 9783798508613
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