Articoli correlati a Modulation of actin dynamics by the S.pneumoniae toxin...
Modulation of actin dynamics by the S.pneumoniae toxin pneumolysin: A novel mechanism beyond pore formation - Brossura
Sinossi
The pneumococcus is one major cause of bacterial meningitis, a wide-spread disease of newborn and immune-compromised individuals, which shows CFRs up to 50% in countries with low medical standards. Bacterial spreading affects the meninges, and the sub-meningeal cortex tissue, whereat the presence of pneumolysin, a major virulence factor of the pneumococcus, is prerequisite for the development of a severe outcome of the infection and associated tissue damage. Pneumolysin belongs to the family of cholesterol-dependent cytolysins, which use membrane-cholesterol as receptor and oligomerize to big aggregates, which induce cell lysis and cell death by disturbance of membrane integrity. This work has revealed a new picture of pneumolysin, whose cell-related properties go beyond pore formation and cell lysis. A direct interaction of the toxin with actin leads to cell-shape remodeling in astrocytes, which potentially disturbes neuronal homeostasis and favors bacterial tissue penetration.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Informazioni sull?autore
Sabrina Hupp (Dipl Biol Univ). Master of Science in Biology (Microbiology, Forensic Medicine and Pharmaceutical Biology) at the University of Würzburg. PhD, Biomedical Science Graduate Program at the University of Würzburg (Rudolf-Virchow-Center, DFG Research Center for Experimental Biomedicine).
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Compra nuovo
Visualizza questo articolo
EUR 56,63
EUR 9,70 per la spedizione da Germania a Italia
Destinazione, tempi e costiRisultati della ricerca per Modulation of actin dynamics by the S.pneumoniae toxin...
Immagini fornite dal venditore
Modulation of actin dynamics by the S.pneumoniae toxin pneumolysin
Editore:
Südwestdeutscher Verlag für Hochschulschriften, 2012
ISBN 10: 3838109910
ISBN 13: 9783838109916
Nuovo
Brossura
Da: moluna, Greven, Germania
Valutazione del venditore 5 su 5 stelle
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Hupp SabrinaSabrina Hupp (Dipl Biol Univ). Master of Science in Biology (Microbiology, Forensic Medicine and Pharmaceutical Biology) at the University of Wuerzburg. PhD, Biomedical Science Graduate Program at the University of Wuerzbur. Codice articolo 5405375
Quantità: Più di 20 disponibili
Immagini fornite dal venditore
Modulation of actin dynamics by the S.pneumoniae toxin pneumolysin
ISBN 10: 3838109910
ISBN 13: 9783838109916
Nuovo
Taschenbuch
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The pneumococcus is one major cause of bacterial meningitis, a wide-spread disease of newborn and immune-compromised individuals, which shows CFRs up to 50% in countries with low medical standards. Bacterial spreading affects the meninges, and the sub-meningeal cortex tissue, whereat the presence of pneumolysin, a major virulence factor of the pneumococcus, is prerequisite for the development of a severe outcome of the infection and associated tissue damage. Pneumolysin belongs to the family of cholesterol-dependent cytolysins, which use membrane-cholesterol as receptor and oligomerize to big aggregates, which induce cell lysis and cell death by disturbance of membrane integrity. This work has revealed a new picture of pneumolysin, whose cell-related properties go beyond pore formation and cell lysis. A direct interaction of the toxin with actin leads to cell-shape remodeling in astrocytes, which potentially disturbes neuronal homeostasis and favors bacterial tissue penetration. 152 pp. Englisch. Codice articolo 9783838109916
Quantità: 2 disponibili
Immagini fornite dal venditore
Modulation of actin dynamics by the S.pneumoniae toxin pneumolysin : A novel mechanism beyond pore formation
Editore:
Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG, 2012
ISBN 10: 3838109910
ISBN 13: 9783838109916
Nuovo
Taschenbuch
Da: AHA-BUCH GmbH, Einbeck, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The pneumococcus is one major cause of bacterial meningitis, a wide-spread disease of newborn and immune-compromised individuals, which shows CFRs up to 50% in countries with low medical standards. Bacterial spreading affects the meninges, and the sub-meningeal cortex tissue, whereat the presence of pneumolysin, a major virulence factor of the pneumococcus, is prerequisite for the development of a severe outcome of the infection and associated tissue damage. Pneumolysin belongs to the family of cholesterol-dependent cytolysins, which use membrane-cholesterol as receptor and oligomerize to big aggregates, which induce cell lysis and cell death by disturbance of membrane integrity. This work has revealed a new picture of pneumolysin, whose cell-related properties go beyond pore formation and cell lysis. A direct interaction of the toxin with actin leads to cell-shape remodeling in astrocytes, which potentially disturbes neuronal homeostasis and favors bacterial tissue penetration. Codice articolo 9783838109916
Quantità: 1 disponibili
Immagini fornite dal venditore
Modulation of actin dynamics by the S.pneumoniae toxin pneumolysin
ISBN 10: 3838109910
ISBN 13: 9783838109916
Nuovo
Taschenbuch
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. Neuware -The pneumococcus is one major cause of bacterial meningitis, a wide-spread disease of newborn and immune-compromised individuals, which shows CFRs up to 50% in countries with low medical standards. Bacterial spreading affects the meninges, and the sub-meningeal cortex tissue, whereat the presence of pneumolysin, a major virulence factor of the pneumococcus, is prerequisite for the development of a severe outcome of the infection and associated tissue damage. Pneumolysin belongs to the family of cholesterol-dependent cytolysins, which use membrane-cholesterol as receptor and oligomerize to big aggregates, which induce cell lysis and cell death by disturbance of membrane integrity. This work has revealed a new picture of pneumolysin, whose cell-related properties go beyond pore formation and cell lysis. A direct interaction of the toxin with actin leads to cell-shape remodeling in astrocytes, which potentially disturbes neuronal homeostasis and favors bacterial tissue penetration.Books on Demand GmbH, Überseering 33, 22297 Hamburg 152 pp. Englisch. Codice articolo 9783838109916
Quantità: 2 disponibili