Coombs test: Clinical, Blood test, Immunohematology, Immunology, Biologic agglutination, Antibody, Red blood cells, Blood, Blood transfusion, Antigen, Cross-matching, Cross-match - Brossura

Brossura

ISBN 10: 6130054513 ISBN 13: 9786130054519

Casa editrice: Alphascript Publishing, 2010

Riassunto

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online.Coombs test (also known as Coombs'' test, antiglobulin test or AGT) refers to two clinical blood tests used in immunohematology and immunology. The two Coombs tests are the direct Coombs test (also known as direct antiglobulin test or DAT), and the indirect Coombs test (also known as indirect antiglobulin test or IAT). In certain diseases or conditions an individual''s blood may contain IgG antibodies that can specifically bind to antigens on the red blood cell (RBC) surface membrane, and their circulating red blood cells (RBCs) can become coated with IgG alloantibodies and/or IgG autoantibodies. Complement proteins may subsequently bind to the bound antibodies. The direct Coombs test is used to detect these antibodies or complement proteins that are bound to the surface of red blood cells; a blood sample is taken and the RBCs are washed (removing the patient''s own plasma) and then incubated with antihuman globulin (also known as Coombs reagent"). If this produces agglutination of RBCs, the direct Coombs test is positive, a visual indication that antibodies (and/or complement proteins) are bound to the surface of red blood cells. "

Dettagli dell?edizione

• Editore: Alphascript Publishing
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 6130054513
• ISBN 13: 9786130054519
• Rilegatura: Copertina flessibile
• Numero di pagine: 92
• Redattore: Miller Frederic P., Vandome Agnes F., McBrewster John
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile