Tumor Microenvironment: Deciphering Tumor Microenvironment for Predicting Outcomes in Head and Neck Cancer - Brossura

Sankar NS, Roshna; Verma, Saloni; Gupta, Shalini

Brossura

ISBN 10: 6207476522 ISBN 13: 9786207476527

Casa editrice: LAP LAMBERT Academic Publishing, 2024

Riassunto

The document systematically explores the tumor microenvironment (TME) within the context of head and neck squamous cell carcinoma (HNSCC), elucidating its multifaceted nature and profound influence on cancer progression and treatment outcomes. Firstly, it delineates the various components constituting the TME, ranging from cellular elements such as cancer-associated fibroblasts, vascular endothelial cells, immune cells (macrophages, neutrophils, lymphocytes, mast cells, natural killer cells), and platelets, to the extracellular matrix and cancer stem cells. This comprehensive overview underscores the complexity of the TME and highlights the diverse interactions among its constituents. Furthermore, the document delves into the role of the TME at different stages of HNSCC pathogenesis, elucidating its involvement in premalignant lesion development and primary tumor progression. It also examines the molecular crosstalk between genetic and epigenetic alterations and their impact on shaping the TME in HNSCC, providing insights into the underlying mechanisms driving cancer aggressiveness.

Dettagli dell'edizione

• Editore: LAP LAMBERT Academic Publishing
• Data di pubblicazione: 2024
• Lingua: Inglese
• ISBN 10: 6207476522
• ISBN 13: 9786207476527
• Rilegatura: Copertina flessibile
• Numero di pagine: 88
• Contatto del produttore: non disponibile
• Persona responsabile: KreGa Onlinehandel GmbH; 4950000000000; info@krega-onlinehandel.de; ; Birkenweg 31; Brakel; 33034; Germania