DEVELOPMENT AND VALIDATION OF ALLOPURINOL: DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF ALLOPURINOL IN BULK DRUG - Brossura

Rani, P. Sudha; Pragathi Bn, Vennila J; T. Srinivasa Reddy, Kavya T

Brossura

ISBN 10: 6207647017 ISBN 13: 9786207647019

Casa editrice: LAP LAMBERT Academic Publishing, 2024

Riassunto

The study is focused to develop and validate HPLC methods for estimation of Allopurinol in tablet dosage form. For routine analytical purpose it is desirable to establish methods capable of analysing huge number of samples in a short time with good robustness, accuracy and precision without any prior separation steps. HPLC method generates large amount of quality data, which serve as highly powerful and convenient analytical tool. The method shows good reproducibility and good recovery. From the specificity studies, it was found that the developed methods were specific for Allopurinol. The proposed methods were found to be simple, sensitive, accurate and precise and showed no interference from the common additives and excipients. The developed method was validated in terms of linearity, accuracy, precision in accordance with the ICH guidelines. Hence the proposed methods can be routinely used for the estimation of Allopurinol in bulk and pharmaceutical dosage forms.

Dettagli dell'edizione

• Editore: LAP LAMBERT Academic Publishing
• Data di pubblicazione: 2024
• Lingua: Inglese
• ISBN 10: 6207647017
• ISBN 13: 9786207647019
• Rilegatura: Copertina flessibile
• Numero di pagine: 60
• Contatto del produttore: non disponibile
• Persona responsabile: KreGa Onlinehandel GmbH; 4950000000000; info@krega-onlinehandel.de; ; Birkenweg 31; Brakel; 33034; Germania