Effects of TiO₂+Ag and SiO₂+Ag nanoparticles on Escherichia coli.: Toxicological study on a model bacterium of the human intestinal flora - Brossura
Sinossi
The proliferation of nanotechnologies, particularly in the food sector, raises concerns about their safety for human health. Due to their nanometric size, these particles cross biological barriers, from the mouth to the intestine. This work assesses the toxicological impact of two nanoparticle (NP) mixtures: TiO₂/Ag and SiO₂/Ag on Escherichia coli, a bacterium representative of the intestinal flora. A clinical strain was isolated by coproculture, identified (API 20E), then exposed to dilutions of NPs (0.125-1024 μg/ml). Petri dishes in Hecktoen medium revealed phenotypic alterations after 24 h incubation at 37°C: decreased growth, reduced colonies, morphological changes, loss of mobility and variations in grouping. At certain concentrations (2 μg/mL TiO₂/Ag, 4 μg/mL SiO₂/Ag), genomic changes were observed (Gram staining), suggesting a potential imbalance in the gut microbiota. These results highlight the need for further study by molecular analysis (DNA extraction, sequencing) to better understand NPs-induced mutations.
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Paperback. Condizione: new. Paperback. The proliferation of nanotechnologies, particularly in the food sector, raises concerns about their safety for human health. Due to their nanometric size, these particles cross biological barriers, from the mouth to the intestine. This work assesses the toxicological impact of two nanoparticle (NP) mixtures: TiO2/Ag and SiO2/Ag on Escherichia coli, a bacterium representative of the intestinal flora. A clinical strain was isolated by coproculture, identified (API 20E), then exposed to dilutions of NPs (0.125-1024 mg/ml). Petri dishes in Hecktoen medium revealed phenotypic alterations after 24 h incubation at 370C: decreased growth, reduced colonies, morphological changes, loss of mobility and variations in grouping. At certain concentrations (2 mg/mL TiO2/Ag, 4 mg/mL SiO2/Ag), genomic changes were observed (Gram staining), suggesting a potential imbalance in the gut microbiota. These results highlight the need for further study by molecular analysis (DNA extraction, sequencing) to better understand NPs-induced mutations. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9786209334108
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Paperback. Condizione: new. Paperback. The proliferation of nanotechnologies, particularly in the food sector, raises concerns about their safety for human health. Due to their nanometric size, these particles cross biological barriers, from the mouth to the intestine. This work assesses the toxicological impact of two nanoparticle (NP) mixtures: TiO2/Ag and SiO2/Ag on Escherichia coli, a bacterium representative of the intestinal flora. A clinical strain was isolated by coproculture, identified (API 20E), then exposed to dilutions of NPs (0.125-1024 mg/ml). Petri dishes in Hecktoen medium revealed phenotypic alterations after 24 h incubation at 370C: decreased growth, reduced colonies, morphological changes, loss of mobility and variations in grouping. At certain concentrations (2 mg/mL TiO2/Ag, 4 mg/mL SiO2/Ag), genomic changes were observed (Gram staining), suggesting a potential imbalance in the gut microbiota. These results highlight the need for further study by molecular analysis (DNA extraction, sequencing) to better understand NPs-induced mutations. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Codice articolo 9786209334108
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Effects of TiO¿+Ag and SiO¿+Ag nanoparticles on Escherichia coli.
Editore:
Our Knowledge Publishing Dez 2025, 2025
ISBN 10: 6209334105
ISBN 13: 9786209334108
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The proliferation of nanotechnologies, particularly in the food sector, raises concerns about their safety for human health. Due to their nanometric size, these particles cross biological barriers, from the mouth to the intestine. This work assesses the toxicological impact of two nanoparticle (NP) mixtures: TiO¿/Ag and SiO¿/Ag on Escherichia coli, a bacterium representative of the intestinal flora. A clinical strain was isolated by coproculture, identified (API 20E), then exposed to dilutions of NPs (0.125-1024 ¿g/ml). Petri dishes in Hecktoen medium revealed phenotypic alterations after 24 h incubation at 37°C: decreased growth, reduced colonies, morphological changes, loss of mobility and variations in grouping. At certain concentrations (2 ¿g/mL TiO¿/Ag, 4 ¿g/mL SiO¿/Ag), genomic changes were observed (Gram staining), suggesting a potential imbalance in the gut microbiota. These results highlight the need for further study by molecular analysis (DNA extraction, sequencing) to better understand NPs-induced mutations.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Englisch. Codice articolo 9786209334108
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