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Mechanisms of Carcinogenesis in Risk Identification: No.116 - Brossura

Vainio, H.; Magee, P. N.; McGregor, D. B.

 
9789283221166: Mechanisms of Carcinogenesis in Risk Identification: No.116

Sinossi

This comprehensive, authoritative volume includes a consensus document drawn up by a working group of international experts in various fields of carcinogenesis. It describes the multistage and multifactorial nature of carcinogenesis, the different mechanisms of action of carcinogens,
epidemiological and laboratory means for their identification, and proposed principles and procedures for their possible use in the prediction and evaluation of carcinogenic risks to humans. Other chapters cover critical molecular targets in chemical carcinogenesis; mechanisms of carcinogenicity;
animal carcinogenicity tests and their interpretations; biological markers in exposed humans; and data analysis and modelling. This work will be a valuable reference for cancer researchers and toxicologists.

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Contenuti

I. Multistage and multifactorial nature of carcinogenesis; II. Mechanisms of action of carcinogens; III. Identification of mechanisms of action of carcinogens; IV. Proposed principles and procedures for using information on mechanisms in evaluating carcinogenic risk to humans; V. References. of mechanisms of action of carcinogens; IV

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