Kilbourne (1973) described the student of influenza as "continually looking back over his shoulder and asking 'what happened?', in the hope that understanding of past events will alert him to the catastrophies ofthe future". Experience suggests the futility of such a hope, since the most predictable feature of influenza is its unpredictability. Nonetheless, the stubborn viabil ity of this hope is strongly affirmed by the many attempts, described and discussed in this volume, to develop a useful and practical representation of influenza virus behavior. I hasten to add, however, that the desired model has yet to be perfected. The existence and usefulness of animal models of infectious diseases of man are well documented. Reproduction of disease by infecting an experimental animal satisfies the third of Koch's four postulates to establish proof of disease causation by a specific bacterium. Animal models also have been extremely useful in studies of the pathogenesis, immunoprophylaxis, and specific therapy of several important diseases, ineluding (with only modest success) influenza. Development of such a model is simple, at least in concept. and can be achieved by one or only a few scientists.
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Background paper: Applications of mathematical models to the epidemiology of influenza: a critique.- I. The epidemiology of influenza key facts and remaining problems.- Discussion.- II. Models of the temporal spread of epidemics.- Discussion.- III. Models of family and small community spread.- Discussion.- IV. Relationship of parameters to the real world.- Discussion.- V. Herd immunity.- Discussion.- VI. Models of geographic spread.- Discussion.- VII. Intervention models and vaccine strategy.- Discussion.- VIII. Recommendations.- Participants.
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Kilbourne (1973) described the student of influenza as continually looking back over his shoulder and asking what happened? , in the hope that understanding of past events will alert him to the catastrophies ofthe future . Experience suggests the futility. Codice articolo 5836154
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Kilbourne (1973) described the student of influenza as 'continually looking back over his shoulder and asking 'what happened ', in the hope that understanding of past events will alert him to the catastrophies ofthe future'. Experience suggests the futility of such a hope, since the most predictable feature of influenza is its unpredictability. Nonetheless, the stubborn viabil ity of this hope is strongly affirmed by the many attempts, described and discussed in this volume, to develop a useful and practical representation of influenza virus behavior. I hasten to add, however, that the desired model has yet to be perfected. The existence and usefulness of animal models of infectious diseases of man are well documented. Reproduction of disease by infecting an experimental animal satisfies the third of Koch's four postulates to establish proof of disease causation by a specific bacterium. Animal models also have been extremely useful in studies of the pathogenesis, immunoprophylaxis, and specific therapy of several important diseases, ineluding (with only modest success) influenza. Development of such a model is simple, at least in concept. and can be achieved by one or only a few scientists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 260 pp. Englisch. Codice articolo 9789401180528
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Kilbourne (1973) described the student of influenza as 'continually looking back over his shoulder and asking 'what happened ', in the hope that understanding of past events will alert him to the catastrophies ofthe future'. Experience suggests the futility of such a hope, since the most predictable feature of influenza is its unpredictability. Nonetheless, the stubborn viabil ity of this hope is strongly affirmed by the many attempts, described and discussed in this volume, to develop a useful and practical representation of influenza virus behavior. I hasten to add, however, that the desired model has yet to be perfected. The existence and usefulness of animal models of infectious diseases of man are well documented. Reproduction of disease by infecting an experimental animal satisfies the third of Koch's four postulates to establish proof of disease causation by a specific bacterium. Animal models also have been extremely useful in studies of the pathogenesis, immunoprophylaxis, and specific therapy of several important diseases, ineluding (with only modest success) influenza. Development of such a model is simple, at least in concept. and can be achieved by one or only a few scientists. Codice articolo 9789401180528
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