DNA Repair - On the Pathways to Fixing DNA Damage and Errors - Rilegato

Rilegato

ISBN 10: 9533076496 ISBN 13: 9789533076492

Casa editrice: IntechOpen, 2011

Riassunto

DNA repair is fundamental to all cell types to maintain genomic stability. A collection of cutting-edge reviews, DNA Repair - On the pathways to fixing DNA damage and errors covers major aspects of the DNA repair processes in a large variety of organisms, emphasizing foremost developments, questions to be solved and new directions in this rapidly evolving area of modern biology. Written by researchers at the vanguard of the DNA repair field, the chapters highlight the importance of the DNA repair mechanisms and their linkage to DNA replication, cell-cycle progression and DNA recombination. Major topics include: base excision repair, nucleotide excision repair, mismatch repair, double-strand break repair, with focus on specific inhibitors and key players of DNA repair such as nucleases, ubiquitin-proteasome enzymes, poly ADP-ribose polymerase and factors relevant for DNA repair in mitochondria and embryonic stem cells. This book is a journey into the cosmos of DNA repair and its frontiers.

Dettagli dell'edizione

• Editore: IntechOpen
• Data di pubblicazione: 2011
• Lingua: Inglese
• ISBN 10: 9533076496
• ISBN 13: 9789533076492
• Rilegatura: Copertina rigida
• Numero di pagine: 394
• Redattore: Storici Francesca
• Contatto del produttore: non disponibile
• Persona responsabile: non disponibile