Articoli correlati a Optimal Control of Drug Administration in Cancer Chemotherap...

Optimal Control of Drug Administration in Cancer Chemotherapy - Rilegato

Martin, Rory; Teo, K. L.

 
9789810214289: Optimal Control of Drug Administration in Cancer Chemotherapy
Rilegato
ISBN 10: 9810214286 ISBN 13: 9789810214289
Casa editrice: World Scientific Pub Co Inc, 1993

Sinossi

This monograph is a study of optimal control applied to cancer chemotherapy, the treatment of cancer using drugs that kill cancer cells. The aim is to determine whether current methods for the administration of chemotherapy are optimal, and if alternative regimens should be considered.The research utilizes the mathematical theory of optimal control, an active research area for many mathematicians, scientists, and engineers. It is of multidisciplinary nature, having been applied to areas ranging from engineering to biomedicine. The aim in optimal control is to achieve a given objective at minimum cost. A set of differential equations is used to describe the evolution in time of the process being modelled, and constraints limit the policies that can be used to attain the objective.In this monograph, mathematical models are used to construct optimal drug schedules. These are treatment guidelines specifying which drug to deliver, when, and at what dose. Many current drug schedules have been derived empirically, based upon “rules of thumb”.The monograph has been structured so that most of the high-level mathematics is introduced in a special appendix. In this way, a scientist can skip the more subtle aspects of the theory and still understand the biomedical applications that follow. However, the text is self-contained so that a deeper understanding of the mathematics of optimal control can be gained from the mathematical appendix.The mathematical models in this book and the associated computer simulations show that low intensity chemotherapy is a better choice of treatment than high intensity chemotherapy, under certain conditions.

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Product Description

Book by Martin Rory Teo K L

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
World Scientific Pub Co Inc
Data di pubblicazione
1993
Lingua
Inglese
ISBN 10 
9810214286
ISBN 13 
9789810214289
Rilegatura
Copertina rigida
Numero di pagine
204
Contatto del produttore
World Scientific Publishing
https://www.worldscientific.com/

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