Science Is Not a Quiet Life: Unravelling the Atomic Mechanism of Haemoglobin - Brossura

Brossura

ISBN 10: 9810230575 ISBN 13: 9789810230579

Casa editrice: World Scientific Pub Co Inc, 1998

Riassunto

Linus Pauling called haemoglobin the most interesting and important of molecules. This important volume shows how X-ray crystallography was used to determine its bewilderingly complex atomic structure and to unravel the stereochemical mechanisms of its respiratory functions. It introduces isomorphous replacement with heavy atoms which led to the first protein structures, haemoglobin and its simpler relative myoglobin. Later papers deal with the stereochemistry of the cooperative effects of haemoglobin, with the relationships between the structures and impaired functions of abnormal haemoglobin, with species adaptation of haemoglobin, and with its action as a drug receptor and as an oxygen sensor. The final papers deal with amino acid repeats which act as polar zippers and their role in certain inherited neurodegenerative diseases.

Dettagli dell'edizione

• Editore: World Scientific Pub Co Inc
• Data di pubblicazione: 1998
• Lingua: Inglese
• ISBN 10: 9810230575
• ISBN 13: 9789810230579
• Rilegatura: Copertina flessibile
• Numero di pagine: 636
• Redattore: Perutz Max
• Contatto del produttore: non disponibile
• Persona responsabile: GPSR Kontakt; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Germania