WHEN YOUR HPLC METHOD GOES WRONG, KNOW WHERE TO LOOK NEXT.
A blank shows a peak.
Pressure suddenly rises.
Your peaks start tailing.
Two compounds co-elute.
Retention time drifts.
Your gradient behaves differently than expected.
What do you check first?
The HPLC Survival Guide: The Lab Detective's Handbook is a practical field manual for diagnosing and troubleshooting real-world reversed-phase HPLC problems in pharmaceutical QC and method development.
Rather than focusing on academic theory alone, this guide uses a problem-first, diagnostic approach: recognize the symptom, investigate the likely causes, and determine the most appropriate next action.
The book contains 14 field missions covering ghost peaks and baseline noise, backpressure, peak shape, stationary-phase selection, mobile-phase control, first-run method development, retention-time drift, resolution and co-elution, gradient problems, UV/DAD detection, calibration and system suitability, peak integration, sample and injection effects, and method transfer and robustness.
It also provides practical reference material, troubleshooting tools, checklists, and guidance for interpreting chromatographic behavior.
Whether you are developing a method, troubleshooting a failed run, investigating an unexpected chromatogram, or working through a QC laboratory problem, this guide is designed to help you move from “What happened?” to “What should I check next?”
Stop guessing. Start diagnosing.
The HPLC Survival Guide: The Lab Detective's Handbook
Mirela Gorjanu Practical Pharma Science™
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Da: California Books, Miami, FL, U.S.A.
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Paperback. Condizione: new. Paperback. When your HPLC method goes wrong, know where to look next.A blank shows a peak. Pressure suddenly rises. Your peaks start tailing. Two compounds co-elute. Retention time drifts. Your gradient behaves differently than expected.What do you check first?The HPLC Survival Guide: The Lab Detective's Handbook is a practical field manual for diagnosing and troubleshooting real-world reversed-phase HPLC problems in pharmaceutical QC and method development. Instead of academic theory alone, it uses a problem-first, diagnostic approach: recognise the symptom, investigate the likely causes, and decide the right next action.14 field missions, including: Ghost peaks, baseline noise and backpressurePeak shape problems, stationary-phase selection and mobile-phase controlFirst-run method development and retention-time driftResolution, co-elution and gradient problemsUV/DAD detection, calibration and system suitabilityPeak integration, sample and injection effectsMethod transfer and robustnessPlus practical reference material, troubleshooting tools and checklists for interpreting chromatographic behaviour.Who it's for: QC analysts, method development scientists, lab technicians and supervisors - anyone who needs to move from "What happened?" to "What should I check next?"Stop guessing. Start diagnosing.Part of the Practical Pharma Science(TM) series - applied knowledge for pharma professionals.- Mirela Gorjanu, Practical Pharma Science(TM) This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9798175215244
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Da: AHA-BUCH GmbH, Einbeck, Germania
Taschenbuch. Condizione: Neu. Neuware - When your HPLC method goes wrong, know where to look next.A blank shows a peak. Pressure suddenly rises. Your peaks start tailing. Two compounds co-elute. Retention time drifts. Your gradient behaves differently than expected.What do you check first The HPLC Survival Guide: The Lab Detective's Handbook is a practical field manual for diagnosing and troubleshooting real-world reversed-phase HPLC problems in pharmaceutical QC and method development. Instead of academic theory alone, it uses a problem-first, diagnostic approach: recognise the symptom, investigate the likely causes, and decide the right next action.14 field missions, including: - Ghost peaks, baseline noise and backpressure- Peak shape problems, stationary-phase selection and mobile-phase control- First-run method development and retention-time drift- Resolution, co-elution and gradient problems- UV/DAD detection, calibration and system suitability- Peak integration, sample and injection effects- Method transfer and robustnessPlus practical reference material, troubleshooting tools and checklists for interpreting chromatographic behaviour.Who it's for: QC analysts, method development scientists, lab technicians and supervisors - anyone who needs to move from 'What happened ' to 'What should I check next 'Stop guessing. Start diagnosing.Part of the Practical Pharma Science(TM) series - applied knowledge for pharma professionals.- Mirela Gorjanu, Practical Pharma Science(TM). Codice articolo 9798175215244
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Paperback. Condizione: new. Paperback. When your HPLC method goes wrong, know where to look next.A blank shows a peak. Pressure suddenly rises. Your peaks start tailing. Two compounds co-elute. Retention time drifts. Your gradient behaves differently than expected.What do you check first?The HPLC Survival Guide: The Lab Detective's Handbook is a practical field manual for diagnosing and troubleshooting real-world reversed-phase HPLC problems in pharmaceutical QC and method development. Instead of academic theory alone, it uses a problem-first, diagnostic approach: recognise the symptom, investigate the likely causes, and decide the right next action.14 field missions, including: Ghost peaks, baseline noise and backpressurePeak shape problems, stationary-phase selection and mobile-phase controlFirst-run method development and retention-time driftResolution, co-elution and gradient problemsUV/DAD detection, calibration and system suitabilityPeak integration, sample and injection effectsMethod transfer and robustnessPlus practical reference material, troubleshooting tools and checklists for interpreting chromatographic behaviour.Who it's for: QC analysts, method development scientists, lab technicians and supervisors - anyone who needs to move from "What happened?" to "What should I check next?"Stop guessing. Start diagnosing.Part of the Practical Pharma Science(TM) series - applied knowledge for pharma professionals.- Mirela Gorjanu, Practical Pharma Science(TM) This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Codice articolo 9798175215244
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Da: preigu, Osnabrück, Germania
Taschenbuch. Condizione: Neu. The HPLC Survival Guide | The Lab Detective's Handbook | Mirela Gorjanu | Taschenbuch | Englisch | 2026 | Amazon Digital Services LLC - Kdp | EAN 9798175215244 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu. Codice articolo 138318383
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