Adhesive Interactions in Normal and Transformed Cells

Lingua: inglese

Editore: Humana Press, Humana Aug 2011, 2011

1617793035 / 9781617793035

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This item is printed on demand - Print on Demand Titel. Neuware -Adhesive Interactions in Normal and Transformed Cells describes the basic mechanisms of the ability of tissue cells to attach to each other and to the extracellular matrix. These adhesive interactions are pivotal regulators of main cellular functions, such as proliferation, survival and migration. The adhesive interactions are involved in embryonic development, regeneration, and also in inflammation and degeneration processes, which are at the basis of many diseases. Serious alterations in cell adhesion caused by the oncogenic transformation play a key role in cancer invasion and metastasis. This volume provides comprehensive information about structural, mechanistic and signaling aspects of adhesive interactions in both normal and cancer cells in comparison. Integration of such aspects of the adhesive process as structure, relation to cell systems of receptors and cytoskeleton, function, signaling pathways, and the alterations in tumor cells constitutes the strongest point of this work. The results of the long-time author¿s research are included in the book. The author was one of pioneers, who used scanning electron microscopy (SEM) to study the cell surface morphology of normal cultured cells and the cells underwent the oncogenic transformation, processes of their attachment to and spreading on the surfaces of a solid substratum, and also surprising ability of the cells to respond to various geometric configurations of the substrata surfaces.Adhesive Interactions in Normal and Transformed Cells has both biological and medical aspects and, therefore, it can be interesting not only for cell biologists, developmental biologists and cancer researchers, but also for physicians. It is intended for researchers, postdocs, undergraduate and graduate students.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Codice articolo 9781617793035

Titolo
Adhesive Interactions in Normal and Transformed Cells
Autore
Yury A. Rovensky
Editore
Humana Press, Humana Aug 2011
Anno di pubblicazione
2011
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
1617793035
ISBN 13
9781617793035
Peso dell'articolo
541 grammi
Dimensioni
241x160x17 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germania

Venditore con 5 stelle

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