Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction

Mark A. Giembycz

ISBN 10: 3034875061 / ISBN 13: 9783034875066

Editore: Birkhäuser Basel, Birkhäuser Basel Mai 2012, 2012

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This item is printed on demand - Print on Demand Titel. Neuware -Building on the existing titles in the 'Airways Smooth Muscle' sub-series, the sixth volume explores physiological and pharmacological processes in the lung in vivo. The various animal models available for studying the bronchospasm and inflammation associated with human asthma are thoroughly reviewed by internationally recognised scientists. Specific chapters focus on the problems of administering drugs to animal airways, the mechanics of assessing lung function in the models, and describe in detail the species used, from rodents to primates. The use of genetically altered animals, an area of particular interest to molecular biologists, is also considered in depth. This up-to-date and extensively referenced work will prove invaluable to pharmacologists, physiologists and other biological scientists at all levels in academia and in the pharmaceutical industry.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 368 pp. Englisch.

Codice articolo 9783034875066

Dati bibliografici

• Titolo: Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction
• Editore: Birkhäuser Basel, Birkhäuser Basel Mai 2012
• Data di pubblicazione: 2012
• Lingua: Inglese
• ISBN 10: 3034875061
• ISBN 13: 9783034875066
• Rilegatura: Taschenbuch
• Condizione: Neu

Descrizione articolo

Riassunto

Building on the existing titles in the "Airways Smooth Muscle" sub-series, the sixth volume explores physiological and pharmacological processes in the lung in vivo. The various animal models available for studying the bronchospasm and inflammation associated with human asthma are thoroughly reviewed by internationally recognised scientists. Specific chapters focus on the problems of administering drugs to animal airways, the mechanics of assessing lung function in the models, and describe in detail the species used, from rodents to primates. The use of genetically altered animals, an area of particular interest to molecular biologists, is also considered in depth. This up-to-date and extensively referenced work will prove invaluable to pharmacologists, physiologists and other biological scientists at all levels in academia and in the pharmaceutical industry.

Contenuti

1. Adrenaline and Noradrenaline.- 2. Acetylcholine.- 3. Histamine.- 4. 5-Hydroxytryptamine.- 5. Prostanoids.- 6. Leukotrienes.- 7. Platelet-Activating Factor.- 8. Purines.- 9. GABA and Benzodiazepines.- 10. Glucocorticoids.