Algorithms in Bioinformatics : A Practical Introduction

Wing-Kin Sung

ISBN 10: 1420070339 / ISBN 13: 9781420070330

Editore: Chapman And Hall/CRC, 2009

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nach der Bestellung gedruckt Neuware - Printed after ordering - This classroom-tested text provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation, precisely defines the corresponding computational problems, and includes detailed examples to illustrate each algorithm. The text covers basic molecular biology concepts, sequence similarity, the suffix tree, sequence databases, sequence and genome alignment, the phylogenetic tree, genome rearrangement, motif finding, the secondary structure of RNA, peptide sequencing, and population genetics. Supplementary material is provided on the author's website and a solutions manual is available for qualifying instructors. Codice articolo 9781420070330

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Titolo: Algorithms in Bioinformatics : A Practical ...

Casa editrice: Chapman And Hall/CRC

Data di pubblicazione: 2009

Legatura: Buch

Condizione: Neu

Descrizione articolo

Riassunto:

Thoroughly Describes Biological Applications, Computational Problems, and Various Algorithmic Solutions

Developed from the author’s own teaching material, Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation and precisely defines the corresponding computational problems. He also includes detailed examples to illustrate each algorithm and end-of-chapter exercises for students to familiarize themselves with the topics. Supplementary material is available at http://www.comp.nus.edu.sg/~ksung/algo_in_bioinfo/

This classroom-tested textbook begins with basic molecular biology concepts. It then describes ways to measure sequence similarity, presents simple applications of the suffix tree, and discusses the problem of searching sequence databases. After introducing methods for aligning multiple biological sequences and genomes, the text explores applications of the phylogenetic tree, methods for comparing phylogenetic trees, the problem of genome rearrangement, and the problem of motif finding. It also covers methods for predicting the secondary structure of RNA and for reconstructing the peptide sequence using mass spectrometry. The final chapter examines the computational problem related to population genetics.

Informazioni sull?autore:

Wing-Kin Sung is an associate professor at the National University of Singapore.