Allergy - Principles and Practice

This volume addresses the progress made in understanding molecular, biologic and immunologic approaches to allergic disease. There are 18 chapters new to this edition, providing information on cytokines and chemokines CD markers, cell surface recepters, and new therapeutics. New classes of biologically active molecules that are integral to the development of allergic inflammation continue to emerge (e.g. chemokines). New knowledge about the role of epithelial cells and the importance of endothelial cells in allergic inflammation are covered in separate chapters.

VOLUME I A. Biology of Allergic Inflammation 1. The Immune System: An Overview 2. Molecular Biology: Basic Mechanisms, Genetic Engineering, and Application to Diseases of the Immune System 3. Principles of Genetics 4. Genetics of Allergic Disease 5. Immunoglobulin Structure & Function 6. The Complement System 7. Control of IgE Synthesis 8. Receptor Structures and Signal Transduction 9. Cellular Adhesion in Inflammation 10. Cytokines in Allergic Inflammation 11. Chemokines in the Biology of Cell Movement and Inflammation 12. Histamine-Releasing Factors and IgE Hetergogeneity 13. Mast Cell Derived Mediators 14. Lipid Mediators of Hypersensitivity and Inflammation 15. Neurogenic Control of Inflammation and Airway Function 16. Biochemical Events in Basophil/Mast Cell Activation and Mediator Release 17. Biology of Lymphocytes 18. Biology of Neutrophils 19. Biology of Eosinophils 20. Biology of Mast Cells 21. Biology of Basophils 22. Biology of Platelets 23. Biology of Monocytes and Macrophages 24. Biology of Epithelial Cells 25. Biology of Endothelial Cells 26. Effector & Regulatory Molecules and Mechanisms in Delayed-Type Hypersensitivity 27. Late Phase Allergic Reactions 28. Pathophysiology of Allergic Inflammation Section B Allergens and Diagnosis of Allergy 29. Aerobiology and Inhalant Allergens 30. Allergenic Extracts 31. Methods in Laboratory Immunology 32. In Vivo Methods for the Study of Allergy: Skin Tests, Techniques, and Interpretation 33. In Vivo Methods for the Study of Allergic Rhinitis: Mucosal Tests, Techniques, and Interpretations 34. Bronchial Challenge Testing Section C Physiology 35. Structure, Function, and Immunology of the Skin 36. Immunologic and Nonimmunologic Lung Defense Mechanisms 37. Structure and Function of Airway Smooth Muscle 38. Development, Structure and Physiology in the Normal Lung and in Asthma 39. Airway Mucus and the Mucociliary System 40. Aerosols 41. Embryology, Anatomy, and Physiology of the Upper Airway Appendices A. Chemokines Table B. CD Molecules Table C. Selected Adhesion Molecules Table VOLUME II Section D. Pharmacology 42. Principles of Pharmacotherapeutics 43. Adrenergic Agents 44. Theophylline and Phosphodiesterase Inhibitors 45. Antihistamines 46. Glucocorticosteroids 47. Cromolyn Sodium and Nedocromil Sodium 48. Cholinergic Mechanisms and Anticholinergic Therapy in Respiratory Diseases 49. Antileukotriene Drugs in the Treatment of Asthma Section E. Clinical Science 50. Cell-Mediated Immunity in Health and Disease 51. Immune Complexes and Allergic Disease 52. Primary Immunodeficiency Diseases 53. Approach to the Patient with Recurrent Infections 54. Immunology of HIV Infection and its Relationship to Allergic Diseases 55. Clinical Significance of IgE 56. Eosinophilia and Eosinophil-Related Disorders 57. Epidemiology and Natural History of Asthma 58. Development & Prevention of Allergic Disease in Childhood 59. Asthma: Definition and Pathogenesis 60. Airway Hyperresponsiveness 61. Pathology of Asthma: A Comparison with COPD 62. Asthma in Infancy and Childhood 63. Asthma in Adults 64. Asthma Guidelines and Outcome 65. Course and Management of Asthma and Allergic Diseases During Pregnancy 66. Exercise-Induced Airway Narrowing 67. Occupational Asthma 68. Allergic Bronchopulmonary Aspergillosis 69. Hypersensitivity Pneumonitis 70. Allergic and Non-Allergic Rhinitis 71. Endoscopy of the Upper Airway 72. Nasal Polyps and Sinusitis 73. Otitis Media 74. Immunotherapy for Inhalant Allergens 75. Insect Allergy 76. Allergy to Natural Rubber Latex 77. Anaphylaxis and Anaphylactoid Reactions 78. Mastocytosis Syndromes 79. Urticaria and Angioedema 80. Atopic Dermatitis 81. Contact Dermatitis 82. Allergic and Immunologic Disorders of the Eye 83. Adverse Reactions to Foods 84. Adverse Reactions to Food and Drug Additives 85. Adverse Reactions to Vaccines 86. Drug Allergy 87. Sensitivity to Aspiring and Nonsteroidal Anti- Inflammatory Drugs 88. Unconventional Theories and Unproven Methods in Allergy Appendix D. Internet Resources