Autoimmune Reactions

. Ed(s): Paul, Sudhir

ISBN 10: 1461272157 / ISBN 13: 9781461272151

Editore: Humana Press Inc., 2012

Editor(s): Paul, Sudhir. Series: Contemporary Immunology. Num Pages: 452 pages, biography. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 23. Weight in Grams: 663. . 2012. Softcover reprint of the original 1st ed. 1999. Paperback. . . . . Books ship from the US and Ireland. Codice articolo V9781461272151

Riassunto:

Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discusses possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their current limitations as unifying explanations of the diseases described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases.

Dalla quarta di copertina: Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discuss possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their current limitations as unifying explanations of the diseases described. In addition, evidence for novel immunological phenomena, including antibody catalysis and the penetration of cells by antibodies, is reviewed, and their possible biological consequences are identified. The book also critically surveys the concepts and research that should eventually permit development of palliatives and cures for autoimmune diseases, as well as approaches to the long-standing problem of self-nonself discrimination by the immune system.

The comprehensive, insightful overview provided in Autoimmune Reactions constitutes the new standard reference for all practicing autoimmunologists, molecular immunologists, cellular and molecular pathologists, and clinical immunologists who need to remain at the cutting-edge of research on autoimmune disease today.

Dati bibliografici

Titolo: Autoimmune Reactions
Casa editrice: Humana Press Inc.
Data di pubblicazione: 2012
Legatura: Brossura
Condizione: New