Biomedical Applications of Acridines | Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

Jan Je¿ek (u. a.)

ISBN 10: 3319639528 / ISBN 13: 9783319639529

Editore: Springer, 2017

Biomedical Applications of Acridines | Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases | Jan Je¿ek (u. a.) | Buch | Progress in Drug Research | xiii | Englisch | 2017 | Springer | EAN 9783319639529 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 109663812

Riassunto:

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.

Dalla quarta di copertina: This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer s disease, Parkinson s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.

Dati bibliografici

Titolo: Biomedical Applications of Acridines | ...
Casa editrice: Springer
Data di pubblicazione: 2017
Legatura: Buch
Condizione: Neu