Cell Cycle Checkpoint Control Protocols

Lingua: inglese

Editore: Humana Press Nov 2003, 2003

1588291154 / 9781588291158

Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

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Venditore AbeBooks dal 11 gennaio 2012

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EUR 139,09

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This item is printed on demand - it takes 3-4 days longer - Neuware -The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress¿for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M¿a transient delay in cell cycle progression will occur. Once the inducing event is properly handled¿ for example, DNA replication is no longer blocked or damaged DNA is repaired¿cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer. 392 pp. Englisch.

Codice articolo 9781588291158

Titolo
Cell Cycle Checkpoint Control Protocols
Autore
Howard B. Lieberman
Editore
Humana Press Nov 2003
Anno di pubblicazione
2003
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
1588291154
ISBN 13
9781588291158
Peso dell'articolo
824 grammi
Dimensioni
241x160x29 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germania

Venditore con 5 stelle

Venditore AbeBooks dal 11 gennaio 2012

Tariffe di spedizione da Germania a U.S.A.

ArticoloDa 5 a 15 giorni lavorativiDa 5 a 15 giorni lavorativi
Primo articoloEUR 23,00EUR 23,00
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BuchWeltWeit Ludwig Meier e.K.

Germania