Riassunto
This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated.
Contenuti
Part I: Vascular Changes in Health and Disease. 1. Analysis of Responses to Human Synthetic Adrenomedullin and Calcitonin Gene-related Peptides in the Hindlimb Vascular Bed of the Cat; H.C. Champion, et al. 2. Effect of Short-Term Treatment with a Monoclonal Antibody to P-Selectin on Balloon Catheter-Induced: Intimal Hyperplasia, Re-Endothelialization, and Attenuation of Endothelial-Dependent Relaxation; D.L. Akers, et al. 3. Differential Regulation of G-Protein Expression by Vasoactive Peptides; M.B. Anand-Srivastava, et al. 4. Endothelin Contraction in Pig Coronary Artery: Receptor Types and Ca2+-Mobilization; A.B. Elmoselhi, A.K. Grover. 5. Activation of the Neutrophil and Loss of Plasma Glutathione During Mg-Deficiency - Modulation by Nitric Oxide Synthase Inhibition; I.T. Mak, et al. 6. Velocity of Translation of Single Actin Filaments (AF) by Myosin Heads from Antigen-Sensitized Airway Smooth Muscle; N.L. Stephens, H. Jiang. 7. Smooth Muscle Contractility and Protein Tyrosine Phosphorylation; A.K. Srivastava, J. St-Louis. 8.Coronary Artery Smooth Muscle in Culture: Migration of Heterogeneous Cell Populations from Vessel Wall; L. Saward, P. Zahradka. 9. An Overview of the Influence of ACE Inhibitors on Fetal-Placental Circulation and Perinatal Development; H.S. Buttar. Part II: Cardiac Mechanisms in Health. 10. Differential Nature of Cross-Talk Among Three G-Coupled Receptors Regulating Adenylyl Cyclase in Rat Cardiomyocytes Chronically Exposed to Receptor Agonists; P.V. Sulakhe, et al. 11. Reversal of Phosphate Induced Decreases in Force by the Benzimadazole Pyridazinone, UD-CG 212CL, in Myofilaments from Human Ventricle; L.D. Fraker, et al. 12. Expression of Fibroblast Growth Factor Receptor-1 in Rat Heart H9c2 Mycoblasts Increases Cell Proliferation; F. Sheikh, et al. 13. Identification of an HMG-Like Protein Involved in Regulation of Na+/H+ Exchanger Expression; H. Wang, et al. 14. Cytochemical nd Immunocytochemical Localization of Na,K-ATPase &agr; Subunit Isoenzymes in the Rat Heart; J. Slezák, et al. 15. Estradiol Modulates the Sodium Pump in the Heart Sarcolemma; A. Džurba, et al. 16. Thyroid Hormones Differentially Affect Sarcoplasmic Reticulum Function in Rat Atria and Ventricles; A. Kaasik, et al. 17. Dietary and Physiological Studies to Investigate the Relationship Between Calcium and Magnesium Signalling in the Mammalian Myocardium; J. Singh, et al. 18. Biological Significance of Phosphorylation and Myristoylation in the Regulation of Cardiac Muscle Proteins; R.V.S. Raju, et al. 19. Contributions of Increased Efficiency and Capacity of Protein Synthesis to Rapid Cardiac Growth; H.E. Morgan, C.J. Beinlich. 20. Cell-Cycle Dependent Anti-FGF-2 Staining of Chicken Cardiac Myocytes: Movement from Chromosomal to Cleavage Furrow- and Midbody-Associated Sites; L. Liu, et al. 21. An Endogenous Positive Inotropic Factor (EPIF) From Porcine Heart: Its Effects on Sarcoplasmic Reticular (SR) Ca2+ Metabolism; J.C. Khatter, et al. Part III: Subcellular Changes in Cardiomyopathies and Heart Failure. 22. Prostaglandins Attenuate Cardiac Contractile Dysfunction Produced by Free Radical Generation but not by Hydrogen Peroxide; M. Karm
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