Chemical Engineering Principles Applied to Medicine : Modeling Physiology, Disease and Drug Delivery

Chemical Engineers are increasingly working on medical problems but so far there is no text that brings together such contributions for inspiring more research and as the basis for advanced courses. This work provides contributions on how Chemical Engineering approaches medical problems, particularly using modelling alongside experimentation and data analysis, to explore medical behaviors. Chapters on modelling the liver, kidney, lungs and skin and associated systems to show how major changes in behavior can be understood and to some extent predicted, are included. This is followed by chapters explaining how engineering principles have been developed to aid diagnosis and treatment of disease such as cancer, diabetes, Von Willibrands disease, and conditions associated with the lungs. The book is of relevance to all Chemical Engineers showing how the discipline is extending to tackle the chemical and physical aspects of disease and human physiology and will also be of interest to clinical staff who wish to see how engineering methodologies can help to integrate the fragmented landscape of medical specialties and in the future move towards decision support tools based on understanding of physiology and disease to aid clinical decision making in the way that is now done in manufacturing.

• Brings together Chemical Engineers with medical experts.
• Inspires young Chemical Engineers to see how and where and how their skill set can be applied to medical problems.
• Within the EFCE Forum on New Technologies Chemical Engineering as Applied in Medicine was seen as an inspiring new area of research.

Prof. David Bogle FREng CEng FIChemE, Pro-Vice-Provost of the Doctoral School and Early Career Researchers, Immediate Past President of the Institution of Chemical Engineers.

David Bogle was born in Australia but undertook his undergraduate education and PhD in Chemical Engineering at Imperial College London. He has been at UCL since 1990 after periods in industry and Australia. He is Deputy Director of the Centre for Process Systems Engineering, a joint research centre of UCL and Imperial College London. He chaired the World Congress of Chemical Engineering in Glasgow in 2005. He is a Fellow of Institution of Chemical Engineers and was elected a Fellow of the UK’s Royal Academy of Engineering in 2005. For 2018-2021 he was Scientific Vice President of the European Federation of Chemical Engineers and is currently Executive Editor for PSE for Chemical Engineering Science. He is the President of the Institution of Chemical Engineers for 2022-23.
As Pro-Vice-Provost at UCL since 2005 he leads the strategy for early career researcher development across all disciplines (doctoral and postdoctoral). He currently teaches Advanced Process Optimisation and introductory Engineering Ethics.
In Process Systems Engineering he has contributed to solution methods for large scale design problems, controllability analysis, global optimization methods, and approaches for Smart Process Manufacturing for chemical and biochemical processes. In Systems Biology he has worked with medical scientists on Systems Engineering of the Liver.
Awards:
IChemE Council Medal
Fellowship of the Royal Academy of Engineering (FREng)

Tomasz Robert Sosnowski, PhD DSc Eng. Full professor in the Faculty of Chemical and Process Engineering, Warsaw University of Technology, Poland.

Member of the Committee of Chemical and Process Engineering of the Polish Academy of Sciences.

Member of the national Council of Scientific Excellence.

Member of the Executive Board of the European Federation of Chemical Engineering (EFCE), and the chairman of the Scientific Section of EFCE "Chemical Engineering as Applied to Medicine".

Main scientific interests:

- dispersed systems, surfactants, multiphase and interfacial phenomena

- aerosols in the environment and medicine

- applications of chemical engineering approach to medicine (mass transfer within the human body, drug delivery systems)

Bibliographic record:

ORCID: 0000-0002-6775-3766.

Co-author of over 100 papers in JCR journals (H=24). Co-author/editor of 2 monographs and co-author of 15 chapters in books.

Listed on 2% top-cited scientists in 2022 according to Stanford University and Scopus (DOI: 10.17632/btchxktzyw.6)

Awards: six individual awards for scientific achievements of the Rector Magnificus of the Warsaw University of Technology (2005-2022).