Chromatin: Structure and Function

Wolffe, A.

ISBN 10: 0127619127 / ISBN 13: 9780127619125

Editore: Academic Press Inc, 1995

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This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In poor condition, suitable as a reading copy. No dust jacket. Water damaged. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,700grams, ISBN:9780127619125. Codice articolo 9625611

Dati bibliografici

Titolo: Chromatin: Structure and Function

Casa editrice: Academic Press Inc

Data di pubblicazione: 1995

Legatura: Rilegato

Condizione: Poor

Edizione: seconda edizione

Descrizione articolo

Riassunto:

The impact of chromatin structure on gene activity and many other nuclear events has become increasingly apparent over the past four years. Progress has been made concerning the structure and function of the nucleoprotein structures regulating transcription, replication, and repair within the eukaryotic chromosome. Important recent advances include the determination of the internal organization of the nucleosome. Findings indicate the histones have unexpected structural similarities to known transcription factors. Similar structures point to similar functions and emphasise the importance of considering both the architectural roles of histones and transcription factors in regulatory complexes. Genetic experiments have introduced a whole new significance both to the histones and to other proteins that control long-range chromosomal compaction and regulate differential gene activity. Modifications to this edition incorporate such new discoveries into the framework of established knowledge. However, the principle aim remains to introduce interested scientists to chromatin. This volume provides the reader with an account of the nature, structure, and assembly of chromatin and its involvement in the processes of DNA transcription, replication, and repair. Constantly interrelating the structure of eurkaryotic DNA with the nuclear processes it undergoes, this book is a must for students and molecular biologists who want to really understand how DNA works.