Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

Peter Igaz

ISBN 10: 3034809530 / ISBN 13: 9783034809535

Editore: Springer Basel, Springer Basel Dez 2015, 2015

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Neuware -MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuseson the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch. Codice articolo 9783034809535

Dati bibliografici

Titolo: Circulating microRNAs in Disease Diagnostics...

Casa editrice: Springer Basel, Springer Basel Dez 2015

Data di pubblicazione: 2015

Legatura: Buch

Condizione: Neu

Descrizione articolo

Riassunto:

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.

Informazioni sull?autore:

Peter Igaz has degrees in medicine and molecular biology. He works as an associate professor in medicine at Semmelweis University Budapest. He is very actively involved in research focusing on the genomics and bioinformatics of endocrine tumors; the study of microRNAs forms a special focus of his research. His research group was among the first to describe tissue microRNA profiles and microRNA biomarkers of malignancy in adrenocortical and adrenomedullary tumors, and circulating microRNAs in adrenocortical tumor patients. His group developed a novel microRNA target prediction algorithm and analyzed pathways involved in adrenal tumors with bioinformatics tools.