Cluster Randomised Trials

Richard J. Hayes

ISBN 10: 1032339586 / ISBN 13: 9781032339580

Editore: Chapman And Hall/CRC Jul 2022, 2022

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This item is printed on demand - it takes 3-4 days longer - Neuware -Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects.In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on randomisation, sample size estimation, and alternative designs, including new material on stepped wedge designs. There is a new section on handling ordinal outcome data, and an appendix with descriptions and/or generating code of the example data sets.Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches. 424 pp. Englisch. Codice articolo 9781032339580

Dati bibliografici

Titolo: Cluster Randomised Trials

Casa editrice: Chapman And Hall/CRC Jul 2022

Data di pubblicazione: 2022

Legatura: Taschenbuch

Condizione: Neu

Edizione: seconda edizione

Descrizione articolo

Riassunto:

Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects.

In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on randomisation, sample size estimation, and alternative designs, including new material on stepped wedge designs. There is a new section on handling ordinal outcome data, and an appendix with descriptions and/or generating code of the example data sets.

Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches.

Informazioni sull?autore:

Richard J. Hayes is affiliated with the Department of Infectious Disease Epidemiology at the London School of Hygiene and Tropical Medicine, UK.

Lawrence H. Moulton is affiliated with the Bloomberg School of Public Health at Johns Hopkins University, USA.