Colon Specific Diloxanide Furoate Delivery using Microspheres

Verma, Siddharth; Shukla, Shailendra

ISBN 10: 3330039841 / ISBN 13: 9783330039841

Editore: LAP Lambert Academic Publishing, 2019

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Codice articolo 42081318

Dati bibliografici

• Titolo: Colon Specific Diloxanide Furoate Delivery using Microspheres
• Editore: LAP Lambert Academic Publishing
• Data di pubblicazione: 2019
• Lingua: Inglese
• ISBN 10: 3330039841
• ISBN 13: 9783330039841
• Rilegatura: Brossura
• Condizione: As New

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Riassunto

The colon is attracting interest as a site where poorly absorbed drug molecule may have an improved bioavailability. This region of the colon is recognized as having a somewhat less hostile environment with less diversity and intensity of activity than the stomach and small intestine. Additionally, the colon has a longer retention time and appears highly responsive to agents that enhance the absorption of poorly absorbed drugs. Apart from retarding or targeting dosage forms, a reliable colonic drug delivery could also be an important starting position for the colonic absorption of per orally applied, undigested, unchanged and fully active peptide drugs.