Combinatorial Computational Biology of RNA: Pseudoknots and Neutral Networks (Paperback or Softback)

Reidys, Christian

ISBN 10: 1489981470 / ISBN 13: 9781489981479

Editore: Springer 9/2/2014, 2014

Combinatorial Computational Biology of RNA: Pseudoknots and Neutral Networks. Codice articolo BBS-9781489981479

Riassunto:

In this monograph, new combinatorial and computational approaches in the study of RNA structures are presented which enhance both mathematics and computational biology. It begins with an introductory chapter, which motivates and sets the background of this research. In the following chapter, all the concepts are systematically developed. The reader will find * integration of more than forty research papers covering topics like, RSK-algorithm, reflection principle, singularity analysis and random graph theory * systematic presentation of the theory of pseudo-knotted RNA structures including their generating function, uniform generation as well as central and discrete limit theorems * computational biology of pseudo-knotted RNA structures, including dynamic programming paradigms and a new folding algorithm * analysis of neutral networks of pseudo knotted RNA structures and their random graph theory, including neutral paths, giant components and connectivity All algorithms presented are freely available through springer.com and implemented in C. A proofs section at the end contains the necessary technicalities. This book will serve graduate students and researchers in the fields of discrete mathematics, mathematical and computational biology. It is suitable as a textbook for a graduate course in mathematical and computational biology.

Dalla quarta di copertina: In this monograph, new combinatorial and computational approaches in the study of RNA structures are presented which enhance both mathematics and computational biology. It begins with an introductory chapter, which motivates and sets the background of this research. In the following chapter, all the concepts are systematically developed. The reader will find* integration of more than forty research papers covering topics like, RSK-algorithm, reflection principle, singularity analysis and random graph theory* systematic presentation of the theory of pseudo-knotted RNA structures including their generating function, uniform generation as well as central and discrete limit theorems* computational biology of pseudo-knotted RNA structures, including dynamic programming paradigms and a new folding algorithm* analysis of neutral networks of pseudoknotted RNA structures and their random graph theory, including neutral paths, giant components and connectivityAll algorithms presented in the book are implemented in C and are freely available through a link on springer.com. A proofs section at the end contains the necessary technicalities.This book will serve graduate students and researchers in the fields of discrete mathematics, mathematical and computational biology. It is suitable as a textbook for a graduate course in mathematical and computational biology.

Dati bibliografici

Titolo: Combinatorial Computational Biology of RNA: ...
Casa editrice: Springer 9/2/2014
Data di pubblicazione: 2014
Legatura: Paperback or Softback
Condizione: New
Tipologia articolo: Book