Combining Human Genetics and Causal Inference to Understand Human Disease and Development

Lingua: inglese

Editore: Cold Spring Harbor Laboratory Press Jan 2022, 2022

1621823814 / 9781621823810

Serie: Libro 34 di 42 - Perspectives CSHL

Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

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Descrizione dell’articolo da parte del venditore

Neuware - In human genetics, causal inference methods leverage large omics data sets and phenotypic information to decipher various cause-and-effect relationships in human health and disease (e.g., smoking and lung cancer). The focus of such work is typically on modifiable variables (e.g., behavior or environmental exposure) that impact disease onset, progression, and outcome. A better understanding of these variables can lead to interventions and therapeutics that have a desirable impact on public health. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines advances in causal inference approaches in human genetics and how they are being used to enhance our understanding of human development and disease. The contributors discuss family-based study designs for causal inference, including twin designs, adoption designs, and in vitro fertilization designs, that separate inherited factors from perinatal environmental exposures. They also review various types of Mendelian randomization--a population-based approach that is growing in utility and popularity--as well as their integration with family-based designs. The use of these approaches to investigate causal mechanisms in specific scenarios (e.g., maternal smoking during pregnancy and ADHD in offspring) is also covered. This volume is therefore an essential read for geneticists, epidemiologists, and all biomedical scientists and public health professionals dedicated to using genetic information to improve human health.…

Codice articolo 9781621823810

Titolo
Combining Human Genetics and Causal Inference to Understand Human Disease and Development
Autore
Rebecca Richmond
Editore
Cold Spring Harbor Laboratory Press Jan 2022
Anno di pubblicazione
2022
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
1621823814
ISBN 13
9781621823810
Peso dell'articolo
748 grammi
Dimensioni
257x178x20 mm
Serie
Libro 34 di 42: Perspectives CSHL

AHA-BUCH GmbH

Einbeck, Germania

Venditore con 5 stelle

Venditore AbeBooks dal 14 agosto 2006

Tariffe di spedizione da Germania a U.S.A.

ArticoloDa 7 a 10 giorni lavorativiDa 5 a 7 giorni lavorativi
Primo articoloEUR 35,00EUR 45,00
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