The Complement System. Questo articolo non è disponibile.The Complement System

This is a comprehensive presentation of all aspects of the complement system, which plays a key role in immunological reactions. The second edition has been thoroughly revised, with additional chapters. It offers the present state of the art, compiled by leading experts in the field. Extensive literature citations offer easy access for those interested in more detail.

Its key role in life preserving functions such as host defense against infections or inflammatory reactions has put the serum complement system at the forefront of biomedical research in both the laboratory and the clinic. This book describes the basic regulation of the complement systems, presenting its biological functions, the target cell receptors for such functions and their interactions with ligands to induce specific cellular responses. The biological functions are also discussed in the context of more complex conditions, for example in host defense, chronic inflammatory disease, graft rejection as well as in adverse reactions to drugs or to artificial surfaces. The book offers the present state-of-the-art compiled by leading experts in the field. Extensive literature citations offer easy access to those interested in more detail.