Current Topics in Complement

Lingua: inglese

Editore: Springer, Springer Jul 2006, 2006

0387322310 / 9780387322315

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This item is printed on demand - Print on Demand Titel. Neuware -Complement has long been regarded as a pivotal effector arm of the innate im-mune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspec-tive. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory cir-cuits. In this respect, scientists from around the world convened at the Third Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 5¿10, 2005), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the 'novel' functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 436 pp. Englisch.…

Codice articolo 9780387322315

Titolo
Current Topics in Complement
Autore
John D. Lambris
Editore
Springer, Springer Jul 2006
Anno di pubblicazione
2006
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
0387322310
ISBN 13
9780387322315
Peso dell'articolo
896 grammi
Dimensioni
241x160x32 mm

buchversandmimpf2000

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