DNA Replication Control in Microbial Cell Factories (Paperback)

Lingua: inglese

Editore: Springer International Publishing AG, Cham, 2014

3319105329 / 9783319105321

Serie: Libro 9 di 20 - SpringerBriefs in Microbiology

Da: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail

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Venditore AbeBooks dal 12 ottobre 2005

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Paperback. This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested.Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cellcycle. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Codice articolo 9783319105321

Titolo
DNA Replication Control in Microbial Cell Factories (Paperback)
Autore
Monika Glinkowska
Editore
Springer International Publishing AG, Cham
Anno di pubblicazione
2014
Condizione
new
Rilegatura
Paperback
Lingua
inglese
ISBN 10
3319105329
ISBN 13
9783319105321
Serie
Libro 9 di 20: SpringerBriefs in Microbiology

Grand Eagle Retail

Bensenville, IL, U.S.A.

Venditore con 5 stelle

Venditore AbeBooks dal 12 ottobre 2005

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